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Patient and Healthcare Provider Perspectives on Disease Burden of Seborrheic Dermatitis in the United States: Results from a National Survey.
Dermatol Ther (Heidelb)
November 2024
Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, IL, USA.
Introduction: Seborrheic dermatitis (SD) is a common, chronic inflammatory skin disease, but the physical and emotional burden of patients with SD experience has not been well characterized.
Methods: The Harris Poll conducted online surveys of US patients and healthcare providers (HCPs) from December 2021 to January 2022.
Results: Almost half of patients reported that SD negatively impacts their emotional and physical well-being "a lot/a great deal"; HCPs underestimate the level of impact on patients.
Ocular Manifestations in Seborrheic Dermatitis Epidemiology, Clinical Features, and Management: A Comprehensive Review.
Cureus
September 2024
College of Medicine, Taibah University, Madinah, SAU.
Seborrheic dermatitis (SD) often leads to ocular manifestations (OM) that are frequently overlooked. This study comprehensively explains the genesis of these ocular issues, which involves a combination of Malassezia overgrowth, changes in sebum production, and inflammatory responses in the body. The periocular region is rich in sebaceous glands, allowing Malassezia to thrive, which can lead to an inflammatory reaction that spreads to the eye surface, causing disorders such as blepharitis, conjunctivitis, keratitis, and ocular surface diseases.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates the role of Demodex mites in the development of eyelid papillomas, focusing on how their presence may influence the tumor's histomorphological characteristics.
- Histomorphological examinations revealed demodectic infection indicators, such as cystic formations and remnants of the mite, in nearly half of the analyzed cases, found within tumor tissues and surrounding structures.
- The findings suggest that these cavity defects created by mite activity may serve as indicators of Demodex infestation, with implications for understanding their impact on various eyelid tumors, including keratoacanthomas and senile keratosis.
More than one shade of pink as a marker of early amelanotic/hypomelanotic melanoma.
J Dermatol
July 2024
Cancer Epidemiology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy.
Article Synopsis
- * The study analyzed 133 digital images of skin lesions diagnosed as either early amelanotic melanoma or non-melanocytic lesions, using assessments by three blinded dermatologists.
- * Results indicated specific features in lesions (like multiple shades of pink and irregular dots) can significantly increase the likelihood of accurate diagnosis of early amelanotic melanoma compared to non-melanoma lesions.
Rapid identification of primary atopic disorders (PAD) by a clinical landmark-guided, upfront use of genomic sequencing.
Allergol Select
October 2024
Center for Child and Adolescent Health, Helios Hospital Krefeld, Academic Hospital of RWTH Aachen, Krefeld.
Article Synopsis
- Primary atopic disorders (PAD) are rare genetic conditions caused by specific gene variants that affect skin and immune function, making diagnosis challenging among common allergic disease cases.
- Identifying PAD requires recognizing clinical red flags like family history and unusual infections, as conventional lab tests are inadequate for definitive diagnosis.
- Whole-genome sequencing (WGS) enhances diagnostic efficiency and accuracy, but requires careful interpretation and collaboration among specialists to effectively manage PAD cases.
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