Investigations in macaques and humans have shown that the anterior intraparietal sulcus (IPS) has an important function in the integration of information from tactile and visual object manipulation. The goal of this study was to investigate the special functional role of the anterior IPS in visuo-tactile matching in humans. We used the "virtual-lesion" technique of repetitive transcranial magnetic stimulation (rTMS) to test the functional relevance of anterior IPS for visuo-tactile crossmodal matching. Two crossmodal (visual encoding and tactile recognition and vice versa) and two unimodal delayed matching-to-sample tests with geometrical patterns were performed by 12 healthy subjects. We determined error rates before and after focal low-frequency rTMS applied over the left anterior IPS, right anterior IPS and vertex. During the manipulation of objects with the right hand, rTMS over the left anterior IPS induced a significant deterioration for visual encoding and tactile recognition, but not for tactile encoding and visual recognition. For the visual and tactile unimodal conditions, no significant alterations in task performance were found. rTMS application over right IPS when manipulating objects with the left hand did not affect crossmodal task performance. In conclusion, we have demonstrated an essential functional role of the left anterior IPS for visuo-tactile matching when manipulating objects with the right hand. However, we found no clear evidence for left IPS involvement in tactile encoding and visual recognition. The differential effect of rTMS on tactile and visual encoding and recognition are not consistently explained by previous concepts of visuo-tactile integration.
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http://dx.doi.org/10.1016/j.brainres.2008.03.075 | DOI Listing |
Autosomal-recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is an early-onset neurodegenerative disease caused by mutations in the SACS gene. The first two mutations were identified in French Canadian populations 20 years ago. The disease is now known as one of the most frequent recessive ataxias worldwide.
View Article and Find Full Text PDFFront Bioeng Biotechnol
November 2024
Department of Prosthodontics, Peking University Hospital of Stomatology, Beijing, Beijing Municipality, China.
Background: Computer-aided design/manufacturing (CAD/CAM) materials are widely used in resin-bonded fixed partial dentures (RBFPDs), but their suitability across different designs has not been fully assessed. This study compares the stress distribution and failure probability of mandibular incisors restored by RBFPDs with various CAD/CAM materials.
Materials And Methods: Finite-element models of single- and double-ended RBFPDs were created using cone-beam computed tomography (CBCT) data.
Clin Exp Dent Res
December 2024
Department of Periodontology, Blekinge Hospital, Karlskrona, Sweden.
Objectives: This study aimed to evaluate potential differences in biofilm accumulation on three different implant surfaces: turned surface (TS), modified surface (MS), and modified surface treated with implantoplasty (IPS), using a within-subject comparison.
Material And Methods: Ten volunteers wore individualized splints containing three titanium implants with different surfaces (TS, MS, and IPS) on each buccal side of the splint. The implant position (anterior, central, and posterior) was randomly assigned among the three implants on each side.
Materials (Basel)
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Department of Biomaterials and Oral Biology, School of Dentistry, University of São Paulo, São Paulo 05508-000, Brazil.
Restorative dentistry often uses ceramic laminate veneers for aesthetic anterior teeth restorations due to their natural appearance and minimal invasiveness. However, the understanding of their clinical performance and how ceramic microstructure and processing affect longevity is limited. This study aimed to address this gap by determining the mechanical behavior, fracture load, and failure modes of CAD-CAM processed laminate veneers made of either lithium-disilicate-based glass ceramic (IPS e.
View Article and Find Full Text PDFBMC Cancer
October 2024
Department of Nuclear Medicine, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, 030001, China.
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