Objective: The objective of the study was to identify the incidence, diagnosis, and therapeutic and histological particularities of ovarian fibromas and fibrothecomas.

Study Design: This was a retrospective study of 24 patients who underwent surgical treatment for ovarian fibromas and fibrothecomas between January 1994 and December 2006. Clinical, ultrasonographic, tumor marker, therapeutic, and histologic data were analyzed.

Results: The mean age of patients was 49 years. Thirteen patients were menopausal. Ultrasonographic findings were ovarian echogenic tumor in 6 cases, hypoechogenic tumor in 12 cases, mixed tumor in 6 cases, and anechogenic tumor in 1 case. Cancer antigen-125 level measured in 21 cases was abnormal in 3 cases. Twenty-one patients underwent laparotomy. Three patients underwent laparoscopy; however, 1 was converted to laparotomy because of a suspected tumor. Histological findings were 16 fibromas and 9 fibrothecomas.

Conclusion: Ovarian fibromas and fibrothecomas are uncommon, accounting for 3.3% of ovarian tumors. These lesions often occur in perimenopausal and menopausal patients. Clinical, ultrasonographic, and tumor marker data remain the best preoperative approach currently available for ovarian tumors. However, the diagnosis remains histological.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajog.2008.03.053DOI Listing

Publication Analysis

Top Keywords

ovarian fibromas
16
fibromas fibrothecomas
12
patients underwent
12
tumor cases
12
clinical ultrasonographic
8
ultrasonographic tumor
8
tumor marker
8
ovarian tumors
8
ovarian
7
tumor
7

Similar Publications

Objective: To characterize the presentation and surgical management of ovarian fibromas among a case series of pediatric and adolescent patients with Gorlin syndrome.

Design: Retrospective case series.

Setting: Tertiary-care hospital.

View Article and Find Full Text PDF

The patient was a 47-year-old woman. She had been aware of abdominal distension for several months and visited our hospital. Contrast CT revealed a 30 cm tumor with uneven contrast effect.

View Article and Find Full Text PDF

Intermittent severe abdominal pain is a medical emergency with multiple possible underlying causes. This case report describes a 30-year-old female experiencing severe pelvic pain alternating between the left and right lower abdomen. The pain was periodic and very intense.

View Article and Find Full Text PDF
Article Synopsis
  • - This case report describes a rare instance of metastatic signet ring carcinoma in the ovary of a 46-year-old Black African woman, occurring alongside a benign fibroma, highlighting the complexity of ovarian lesions.
  • - The patient experienced significant abdominal swelling and was found to have a large mass in the right ovary, along with signs of metastasis in the lungs and liver, as indicated by imaging and elevated tumor markers (CA 125 and CA 19-9).
  • - Surgical intervention involved a total abdominal hysterectomy and bilateral salpingo-oophorectomy, revealing a mix of spindle cells and signet ring cells in the ovarian tissues, illustrating the unique histological findings associated with this case.
View Article and Find Full Text PDF

Ovarian fibromatosis is a rare non-neoplastic condition that causes ovarian enlargement in women, typically around the age of 25. This enlargement is due to the proliferation of the collagen-producing ovarian stroma. On T2-weighted MRI, a key diagnostic feature of ovarian fibromatosis is the 'black garland sign,' characterized by multilobulated very low signal intensity along the ovarian surface.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!