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The mortality analysis of primary prevention patients receiving a cardiac resynchronization defibrillator (CRT-D) or implantable cardioverter-defibrillator (ICD) according to guideline indications in the improve SCA study.
J Cardiovasc Electrophysiol
August 2021
Fu Wai Hospital Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Background: In primary prevention (PP) patients the utilization of implantable cardioverter-defibrillators (ICD) and cardiac resynchronization therapy-defibrillators (CRT-D) remains low in many geographies, despite the proven mortality benefit.
Purpose: The objective of this analysis was to examine the mortality benefit in PP patients by guideline-indicated device type: ICD and CRT-D.
Methods: Improve sudden cardiac arrest was a prospective, nonrandomized, nonblinded multicenter trial that enrolled patients from regions where ICD utilization is low.
A Population-Based Study of Adherence to Guideline Recommendations and Appropriate-Use Criteria for Implantable Cardioverter Defibrillators.
Can J Cardiol
December 2018
Mazankowski Alberta Heart Institute, University of Alberta, Division of Cardiology, Edmonton, Alberta, Canada. Electronic address:
Studies evaluating physician adherence to guideline recommendations for implantable cardioverter defibrillator (ICD) therapy are sparse, and none exist for the application of appropriate-use criteria (AUC) in clinical practice. As part of a quality improvement initiative, a review of all ICD procedures was performed from January 1, 2015 to December 31, 2016 in Alberta, Canada, to evaluate the proportion of patients receiving appropriate ICD therapy and to identify reasons for nonadherence. Our device-implant process involves an electrophysiologist or implanting cardiologist evaluation, reminders of ICD eligibility criteria on the device requisition, and peer-review consensus.
View Article and Find Full Text PDFMechanism underlying catecholaminergic polymorphic ventricular tachycardia and approaches to therapy.
J Electrocardiol
February 2012
Division of Cardiology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited arrhythmia syndrome characterized by VT induced by adrenergic stress in the absence of structural heart disease and high incidence of sudden cardiac death. The diagnosis is made based on reproducible ventricular tachyarrhythmias including bidirectional VT and polymorphic VT during exercise testings. Two causative genes of CPVT have been identified: RYR2, encoding the cardiac ryanodine receptor (RyR2) Ca(2+) release channel, and CASQ2, encoding cardiac calsequestrin.
View Article and Find Full Text PDFThe ACC/AHA/HRS 2008 guidelines for device-based therapy of cardiac rhythm abnormalities: their relevance to the cardiologist, internist and family physician.
J Invasive Cardiol
May 2009
Stony Brook Arrhythmia Study and Sudden Death Prevention Center, Cardiology Division, Department of Medicine, Stony Brook University, Stony Brook, New York, USA.
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