A dosimetry intercomparison between the boron neutron capture therapy groups of the Massachusetts Institute of Technology (MIT) and the Comisión Nacional de Energía Atómica (CNEA), Argentina was performed to enable combined analyses of NCT patient data between the different centers. In-air and dose versus depth measurements in a rectangular water phantom were performed at the hyperthermal neutron beam facility of the RA-6 reactor, Bariloche. Calculated dose profiles from the CNEA treatment planning system NCTPlan that were calibrated against in-house measurements required normalizations of 1.0 (thermal neutrons), 1.13 (photons), and 0.74 (fast neutrons) to match the dosimetry of MIT.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1118/1.2884856 | DOI Listing |
Pathogens
December 2024
Research Group Biomarkers for Infectious Diseases, TWINCORE Centre for Experimental and Clinical Infection Research, 30625 Hannover, Germany.
Vaccination against hepatitis B virus (HBV) is the most cost-efficient measure to prevent infection. Still, vaccination coverage among adults in Central Asia, including Kyrgyzstan, remains suboptimal, and data about immune responses to HBV vaccination are lacking. HBV vaccination is given as three injections, whereby the second and third doses are given 1 and 6 months after the first (0-1-6 scheme).
View Article and Find Full Text PDFBrain Sci
December 2024
Movement Disorders Unit, Neurology Department, Complex Hospitalari Moisès Broggi, 08970 Sant Joan Despí, Barcelona, Spain.
Introduction: Randomized clinical trials should be complemented with data from real-world studies. We report our long-term experience with safinamide in a movement disorders unit.
Methods: This retrospective study included patients with Parkinson's disease (PD) treated with safinamide in our unit from February 2016 to May 2022 under routine clinical practice.
Phys Med Biol
January 2025
OncoRay - National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, Helmholtz-Zentrum Dresden - Rossendorf, Dresden, Sachsen, 01307, GERMANY.
Mathematical modeling can offer valuable insights into the behavior of biological systems upon treatment. Different mathematical models (empirical, semi-empirical, and mechanistic) have been designed to predict the efficacy of either hyperthermia (HT), radiotherapy (RT), or their combination. However, mathematical approaches capable of modeling cell survival from shared general principles for both mono-treatments alone and their co-application are rare.
View Article and Find Full Text PDFOptica
December 2024
Department of Medical Physics and Biomedical Engineering, University College London, London, WC1E 6BT, UK.
X-ray dark-field imaging highlights sample structures through contrast generated by sub-resolution features within the inspected volume. Quantifying dark-field signals generally involves multiple exposures for phase retrieval, separating contributions from scattering, refraction, and attenuation. Here, we introduce an approach for non-interferometric X-ray dark-field imaging that presents a single-parameter representation of the sample.
View Article and Find Full Text PDFBMC Public Health
December 2024
Medical College of Tibet University, No. 10 East Zangda Road,Chengguan District, Lhasa, 850000, China.
Background: The prevalence of hypertension among the Tibetan population in Tibet is higher than in other regions of China, and there is a lack of unified epidemiological surveys. This study aims to conduct a standardized epidemiological investigation to assess the current status of hypertension among the Tibetan population, as well as to explore the dose-response relationship between cholesterol (TC), triglyceride glucose index (TyG), triglyceride glucose-body mass index (TyG-BMI), and hypertension in this population.
Methods: From June 2020 to July 2023, a total of 5042 Tibetans aged 18 to 80 years from three cities and one region in Tibet were randomly sampled for the study.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!