AI Article Synopsis

  • Restorative proctocolectomy and ileal pouch-anal anastomosis (IPAA) is the preferred surgery for ulcerative colitis but is complex and carries risks, prompting a study on its early outcomes in Denmark from 2001 to 2005.
  • A total of 385 patients were included, with a mean hospital stay of 13.5 days; 24% were readmitted and 8% required re-operations within 30 days, while the mortality rate was 0.3%.
  • The study suggests that IPAA procedures should be concentrated in fewer centers to address high early complication rates and the steep learning curve associated with the surgery.

Article Abstract

Introduction: Restorative proctocolectomy and ileal pouch-anal anastomosis (IPAA) has become the operation of choice for patients with ulcerative colitis and familial polyposis. However, the procedure is complex with a long learning curve, and carries a risk of both early and late complications. The purpose of this study was to evaluate the early outcomes (within 30 days after surgery) and organisation of IPAA surgery in Denmark between January 2001 and December 2005.

Materials And Methods: IPAA patients >18 years old were drawn from the Danish National Patient Registry from 2001 through 2005. Hospital stay and the primary operation were recorded as well as re-operations and readmissions within the first 30 postoperative days. Mortality was recorded from the National Civic Register.

Results: 385 patients underwent IPAA surgery during the study period (77/year) in six centres. One centre performed 31% of the operations. The mean postoperative hospital stay (primary - and readmission within 30 days) was 13.5 days. 24% were readmitted within 30 days and 8% were re-operated. The mortality rate was 0.3%.

Conclusion: Based upon the limited number of operations, the high risk of early readmissions and re-operations, the well-known steep learning curve and the potential improvement with the technically demanding laparoscopic technique, a reorganisation of the procedure to fewer centres is suggested.

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