Neural sequences: experimental evidence and deductive principles.

Funct Neurol

Verbochronometry Laboratory, IRCCS S. Maugeri Foundation, and Department of Bioengineering, University of Pavia, Veruno, Italy.

Published: August 2008

Comprehensive study of brain performances implies reference to sequences of repetitive functional elements (events). In this particular experimental field, these are sequences of psychomotor reactions and particularly verbal reactions with different modalities of stimuli and pre-established intervals before responding. The organization of these sequences or temporal cycles is based on different sets of stimuli and series of processes that are measured through parameters related to trials that activate the central mechanism of working memory. Monitoring of sequences in rehabilitation training is performed through analysis of the course of the intermediary oscillations between the onset and the end (conventionally established) of treatment. Knowledge of these oscillations provides useful information on the nature of facilitating or fatiguing effects of training procedures.

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