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Heart rate variability biofeedback in a global study of the most common coherence frequencies and the impact of emotional states.
Sci Rep
January 2025
HeartMath Institute, Boulder Creek, CA, 95006, USA.
This global study analyzed data from the largest dataset ever studied in the Heart Rate Variability (HRV) biofeedback field, comprising 1.8 million user sessions collected from users of a mobile app during 2019 and 2020. We focused on HRV Coherence, which is linked to improved emotional stability and cognitive function.
View Article and Find Full Text PDFInhibitors of NADH-O-methylquinone compound a class of antitubercular drugs.
Mol Divers
January 2025
Department of Laboratory Medicine, The Fourth People's Hospital of Nanhai District of Foshan City, Foshan, 528000, Guangdong, China.
Disruption of the mycobacterial redox homeostasis leads to irreversible stress induction and cell death. Hydroquinone scaffolds, as a new type of redox cycling anti-tuberculosis chemotypes, exhibit potent bactericidal activity against non-replicating, nutrient-deprived phenotypically drug-resistant bacteria. Evidences from microbiological, biochemical, and genetic studies indicate that the redox-driven mode of action relies on the reduction of quinones by type II NADH dehydrogenase (NDH2), generating reactive oxygen species (ROS) of bactericidal level.
View Article and Find Full Text PDF-Lyophilized Fruit Extract Attenuated Acute Redox-Homeostatic Imbalance via Mutagenic and Oxidative Stress Modulation in Mice Model on Gentamicin-Induced Nephrotoxicity.
Pharmaceuticals (Basel)
January 2025
Department of Chemistry and Biochemistry, Medical Faculty, Trakia University, 11 Armeiska Str., 6000 Stara Zagora, Bulgaria.
Gentamicin (GM) administration is associated with decreased metabolism, increased oxidative stress, and induction of nephrotoxicity. L., containing flavonoids, anthocyanins, and phytosterols, possesses antioxidant and anti-inflammatory potential.
View Article and Find Full Text PDFPharmacodynamic Profiling of Amoxicillin: Targeting Multidrug-Resistant Gram-Positive Pathogens and in Canine Clinical Isolates.
Antibiotics (Basel)
January 2025
Developmental and Reproductive Toxicology Research Group, Korea Institute of Toxicology, Daejeon 34114, Republic of Korea.
The rising threat of antimicrobial resistance (AMR) is a global concern in both human and veterinary medicine, with multidrug-resistant (MDR) pathogens such as and presenting significant challenges. : This study evaluates the effectiveness of amoxicillin against these MDR pathogens in canine isolates using pharmacokinetic and pharmacodynamic parameters. : Minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), and mutation prevention concentration (MPC) were assessed.
View Article and Find Full Text PDFInvasive Traits of and : Insights from Distribution Modeling, Reproductive Success, and Morpho-Structural Analysis.
Biology (Basel)
January 2025
Faculty of Biology, University of Bucharest, 1-3 Intr. Portocalelor, 060101 Bucharest, Romania.
Understanding the drivers of invasive species' success is essential for predicting and managing their ecological impacts. , a South American species first recorded in Bucharest in 2015, is currently expanding into urban and peri-urban areas of Romania, raising concerns about its invasive potential. This study provides a comprehensive assessment of its invasiveness by integrating species distribution modeling, a reproductive trait analysis, and morpho-structural evaluations.
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