Background: Cardiac autonomic nervous system (ANS) dysfunction in Huntington's disease (HD) might affect both the sympathetic and parasympathetic branch of the ANS.
Results And Conclusions: The pattern of linear heart rate variability we found in mid stage HD patients points towards a predominately reduced cardiovagal modulation compared with healthy subjects, which might influence HD patients' susceptibility for cardiovascular complications such as syncopes and cardiac arrhythmias.
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http://dx.doi.org/10.1111/j.1468-1331.2008.02173.x | DOI Listing |
Front Physiol
January 2025
Institute of Biomedical Electronics, Vienna University of Technology, Vienna, Austria.
Neuromodulation comes into focus as a non-pharmacological therapy with the vagus nerve as modulation target. The auricular vagus nerve stimulation (aVNS) has emerged to treat chronic diseases while re-establishing the sympathovagal balance and activating parasympathetic anti-inflammatory pathways. aVNS leads still to over and under-stimulation and is limited in therapeutic efficiency.
View Article and Find Full Text PDFFront Sports Act Living
December 2024
Geriatric Medicine Research, Dalhousie University & Nova Scotia Health, Halifax, NS, Canada.
Engaging in muscle strengthening activities (e.g., resistance training) at least twice/week is promoted by (Inter)national movement guidelines.
View Article and Find Full Text PDFMov Disord Clin Pract
December 2024
Department of Neurology, IRCCS Humanitas Research Hospital, Rozzano, Italy.
Background: The role played by sympathetic and parasympathetic autonomic branches in patients with Parkinson's disease carrying variants in the GBA1 gene (GBA-PD) is still elusive.
Objectives: To characterize cardiovascular autonomic function in GBA-PD and I-PD patients with early and mid-stage disease.
Methods: These assessments were performed: cardiovascular autonomic tests, analysis of heart rate and blood pressure variability, cardiac noradrenergic imaging.
Med Sci Sports Exerc
October 2024
School of Health and Exercise Sciences, University of British Columbia, Kelowna, BC, CANADA.
Purpose: Research on intermittent training has mainly focused on the effects of exercise intensity while overlooking the specific impact of the modulations associated with alternating exercise and recovery. This study investigated how the frequency of modulations during moderate-intensity exercise affects post-exercise vagal reactivation.
Methods: Healthy, active females and males aged 18-39 years were recruited for the study.
Eur J Appl Physiol
October 2024
School of Health and Exercise Sciences, University of British Columbia, 1147 Research Road, Kelowna, BC, V1V 1V7, Canada.
Purpose: Exercise training requires the careful application of training dose to maximize adaptation while minimizing the risk of illness and injury. High-intensity interval training (HIIT) is a potent method for improving health and fitness but generates substantial autonomic imbalance. Assuming a supine posture between intervals is a novel strategy that could enhance physiological readiness and training adaptations.
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