AI Article Synopsis
- A method has been created using cinchonidine (or cinchonine) ammonium salts to react with nitroolefins.
- This process takes place in the presence of Cs2CO3.
- The result is the production of optically active isoxazoline N-oxides with high enantiomeric excess (ee) and good diastereomeric values (de).
Article Abstract
The reaction of cinchonidine (cinchonine)-derived ammonium salts with nitroolefins in the presence of Cs2CO3 to afford optically active isoxazoline N-oxides with excellent ee and high de values has been developed.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/b716468h | DOI Listing |
Publication Analysis
Top Keywords
isoxazoline n-oxides
8
highly enantioselective
4
enantioselective synthesis
4
synthesis isoxazoline
4
n-oxides reaction
4
reaction cinchonidine
4
cinchonidine cinchonine-derived
4
cinchonine-derived ammonium
4
ammonium salts
4
salts nitroolefins
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!