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BMC Infect Dis
January 2025
Infectious Diseases Research Center, Birjand University of Medical Sciences, Birjand, P.O. Box: 9717853577, Iran.
Background: Toxoplasma gondii (T. gondii) is the most successful obligate protozoan that can infect warm-blooded vertebrate hosts. Some researchers suggest that the presence of Toxoplasma cysts in the brain can lead to mental disorders.
View Article and Find Full Text PDFParasitol Int
December 2024
Department of Veterinary Pathobiology, College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, College Station, TX, USA. Electronic address:
Zoonotic parasitic infections can affect both animal and human health, while also having food safety and economic implications. These pathogens can also pose occupational risks for certain groups, including veterinary professionals, animal handlers, and butchers. This study was conducted in the district of Swabi located in the Khyber Pakhtunkhwa Province of northwestern Pakistan.
View Article and Find Full Text PDFDrug Des Devel Ther
December 2024
Chemistry of Natural Compounds Department, Pharmaceutical and Drug Industries Research Institute, National Research Center, Dokki, Cairo, Egypt.
Introduction: Toxoplasmosis, a zoonotic infection caused by the apicomplexan parasite , affects a significant portion of the global human population. This condition, particularly dangerous for pregnant women and immunocompromised individuals, currently lacks effective treatment options.
Methods: Eighteen coumarin-based derivatives were synthesized, comprising coumarin-chalcone hybrids (5a-i) and coumarin-pyrazoline hybrids (6a-i).
Acta Trop
December 2024
Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang, China; Zhejiang Key Lab of Vaccine, Infectious Disease Prevention and Control, Hangzhou, Zhejiang, China. Electronic address:
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