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Background: Toxoplasma gondii (T. gondii) is the most successful obligate protozoan that can infect warm-blooded vertebrate hosts. Some researchers suggest that the presence of Toxoplasma cysts in the brain can lead to mental disorders.

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ELISA based seroprevalence and risk factors for three zoonotic parasites (Toxoplasma gondii, Echinococcus granulosus and Trichinella spiralis) in humans in Khyber Pakhtunkhwa, Pakistan.

Parasitol Int

December 2024

Department of Veterinary Pathobiology, College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, College Station, TX, USA. Electronic address:

Zoonotic parasitic infections can affect both animal and human health, while also having food safety and economic implications. These pathogens can also pose occupational risks for certain groups, including veterinary professionals, animal handlers, and butchers. This study was conducted in the district of Swabi located in the Khyber Pakhtunkhwa Province of northwestern Pakistan.

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Identification of Coumarin-Chalcone and Coumarin-Pyrazoline Derivatives as Novel Anti- Agents.

Drug Des Devel Ther

December 2024

Chemistry of Natural Compounds Department, Pharmaceutical and Drug Industries Research Institute, National Research Center, Dokki, Cairo, Egypt.

Introduction: Toxoplasmosis, a zoonotic infection caused by the apicomplexan parasite , affects a significant portion of the global human population. This condition, particularly dangerous for pregnant women and immunocompromised individuals, currently lacks effective treatment options.

Methods:  Eighteen coumarin-based derivatives were synthesized, comprising coumarin-chalcone hybrids (5a-i) and coumarin-pyrazoline hybrids (6a-i).

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Seroprevalence of Toxoplasma gondii infection among pregnant women in the first trimester in China.

Acta Trop

December 2024

Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang, China; Zhejiang Key Lab of Vaccine, Infectious Disease Prevention and Control, Hangzhou, Zhejiang, China. Electronic address:

Article Synopsis
  • * A study conducted in Hangzhou, China, found the seroprevalence of anti-T. gondii antibodies among pregnant women in their first trimester to be 3.6%, showing a significant increase from previous years.
  • * The highest seroprevalence was in the 41-49 age group (10.7%) and the Qiantang District (11.1%), indicating a need for targeted health education in these demographics.
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