Total internal reflection resonance light scattering at solid/liquid interfaces.

J Pharm Biomed Anal

Department of Chemistry and The Key Laboratory of Analytical Sciences of the Ministry of Education, College of Chemistry and Chemical Engineering, Xiamen University, Siming South Road 422, Xiamen 361005, China.

Published: August 2008

Total internal reflection (TIR) technique is an interface-specific tool and resonance light scattering (RLS) is of high sensitivity. The combination of both approaches is introduced into the solid/liquid interface for the first time. The behaviors of mixture of TPPS and BSA at the interface have been studied with total internal reflection resonance light scattering (TIR-RLS). The preliminary experimental results indicate that TIR-RLS is a good approach to study the interaction and distinguish the states of macromolecules at the solid/liquid interface.

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http://dx.doi.org/10.1016/j.jpba.2008.03.029DOI Listing

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