Experienced forensic pathologists and examiners may be familiar with the phenomenon of postmortem iris color change; however, only Knight, Simpson's forensic medicine, Arnold, London, 1997; Ref. 1 and Saukko and Knight, Knight's forensic pathology, 3rd ed., Arnold, London, 2004; Ref. 2 have referred to it in the literature, and to date, there have been no published scientific research studies on this taphonomic artifact. A controlled experiment was conducted of postmortem changes to isolated Sus scrofa eyes. The eyes (n = 137) were separated into three groups and each sample was observed for 3-day postmortem at a different temperature. In addition, a Sus scrofa head was obtained to observe postmortem changes of eyes in situ. All isolated blue eyes in the experiment, at room temperature and higher, changed to brown/black within 48 h. The in situ blue eye, at room temperature, turned brown/black within 72 h. If iris color consistently changes postmortem in humans, then this taphonomic artifact must be incorporated into victim identification protocol, including disaster victim identification software, and autopsy reports to prevent inaccurate victim identification and inappropriate exclusion from the identification process.
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http://dx.doi.org/10.1111/j.1556-4029.2008.00729.x | DOI Listing |
BMC Genomics
January 2025
Shaanxi Key Laboratory of Qinling Ecological Security, Shaanxi Institute of Zoology, Xi'an, 710032, China.
Background: The relict gull (Larus relictus, Charadriiformes, Laridae) classified as vulnerable in the IUCN Red List is defined as a first-class national protected bird in China. However, our knowledge of the evolutionary history of L. relictus is limited.
View Article and Find Full Text PDFHeliyon
July 2024
D-Eye Srl, Padova, 35131, Italy.
Widespread screening is crucial for the early diagnosis and treatment of glaucoma, the leading cause of visual impairment and blindness. The development of portable technologies, such as smartphone-based ophthalmoscopes, able to image the optical nerve head, represents a resource for large-scale glaucoma screening. Indeed, they consist of an optical device attached to a common smartphone, making the overall device cheap and easy to use.
View Article and Find Full Text PDFTransl Vis Sci Technol
January 2025
Institute of the Electrical and Biomedical Engineering, UMIT TIROL - Private University for Health Sciences and Health Technology, Hall in Tyrol, Austria.
Purpose: To extract conjunctival bulbar redness from standardized high-resolution ocular surface photographs of a novel imaging system by implementing an image analysis pipeline.
Methods: Data from two trials (healthy; outgoing ophthalmic clinic) were collected, processed, and used to train a machine learning model for ocular surface segmentation. Various regions of interest were defined to globally and locally extract a redness biomarker based on color intensity.
Nat Commun
January 2025
NIHR Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust & University College London Institute of Ophthalmology, London, UK.
Few metrics exist to describe phenotypic diversity within ophthalmic imaging datasets, with researchers often using ethnicity as a surrogate marker for biological variability. We derived a continuous, measured metric, the retinal pigment score (RPS), that quantifies the degree of pigmentation from a colour fundus photograph of the eye. RPS was validated using two large epidemiological studies with demographic and genetic data (UK Biobank and EPIC-Norfolk Study) and reproduced in a Tanzanian, an Australian, and a Chinese dataset.
View Article and Find Full Text PDFSmall Methods
December 2024
Institute of Translational Medicine, Nanjing Drum Tower Hospital, School of Biological Science and Medical Engineering, Southeast University, Nanjing, 210096, China.
Colored contact lenses have gained popularity among young individuals owing to their ability to alter the appearance of the wearer's eyes. However, conventional lenses containing chemical dyes are susceptible to detachment of the pigment layer, which can lead to corneal damage. In this research, a novel cellulose-based structural color contact lens (SCCL) is presented that enhances aesthetic appeal via a cholesteric liquid crystal (CLC) layer.
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