The present study analyzed apical translucency and periodontal recession on single-rooted teeth in order to generate age-at-death estimations using two inverse calibration methods and one Bayesian method. The three age estimates were compared to highlight inherent problems with the inverse calibration methods. The results showed that the Bayesian analysis reduced severity of several problems associated with adult skeletal age-at-death estimations. The Bayesian estimates produced a lower overall mean error, a higher correlation with actual age, reduced aging bias, reduced age mimicry, and reduced the age ranges associated with the most probable age as compared to the inverse calibration methods for this sample. This research concluded that periodontal recession cannot be used as a univariate age indicator, due to its low correlation with chronological age. Apical translucency yielded a high correlation with chronological age and was concluded to be an important age indicator. The Bayesian approach offered the most appropriate statistical analysis for the estimation of age-at-death with the current sample.
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http://dx.doi.org/10.1111/j.1556-4029.2008.00713.x | DOI Listing |
PLoS Comput Biol
January 2025
Department of Mechanical Engineering, University of California Riverside, Riverside, California, United States of America.
Respiratory diseases represent a significant healthcare burden, as evidenced by the devastating impact of COVID-19. Biophysical models offer the possibility to anticipate system behavior and provide insights into physiological functions, advancements which are comparatively and notably nascent when it comes to pulmonary mechanics research. In this context, an Inverse Finite Element Analysis (IFEA) pipeline is developed to construct the first continuously ventilated three-dimensional structurally representative pulmonary model informed by both organ- and tissue-level breathing experiments from a cadaveric human lung.
View Article and Find Full Text PDFMar Pollut Bull
January 2025
Ecology & Environment Research Group, Centre for Water Resources Development and Management, Kozhikode, India.
This study evaluates the influence of water current and suspended sediment concentration (SSC) on microplastic distribution in various mixing regimes of the Ashtamudi estuary, India. Microplastic abundance ranged from 3.2 to 53 items/L, with highest concentrations observed near the confluence of the river and the sea.
View Article and Find Full Text PDFComput Biol Med
January 2025
Institute for Neuroradiology, TUM University Hospital, School of Medicine and Health, Technical University of Munich (TUM), Munich, Germany.
Accurate calibration of finite element (FE) models is essential across various biomechanical applications, including human intervertebral discs (IVDs), to ensure their reliability and use in diagnosing and planning treatments. However, traditional calibration methods are computationally intensive, requiring iterative, derivative-free optimization algorithms that often take days to converge. This study addresses these challenges by introducing a novel, efficient, and effective calibration method demonstrated on a human L4-L5 IVD FE model as a case study using a neural network (NN) surrogate.
View Article and Find Full Text PDFSensors (Basel)
December 2024
Department of Mechanical Engineering, Brigham Young University, Provo, UT 84602, USA.
Flexible high-deflection strain gauges have been demonstrated to be cost-effective and accessible sensors for capturing human biomechanical deformations. However, the interpretation of these sensors is notably more complex compared to conventional strain gauges, particularly during dynamic motion. In addition to the non-linear viscoelastic behavior of the strain gauge material itself, the dynamic response of the sensors is even more difficult to capture due to spikes in the resistance during strain path changes.
View Article and Find Full Text PDFJ Mech Behav Biomed Mater
December 2024
Institute of Continuum Mechanics and Biomechanics, Department of Mechanical Engineering, Friedrich-Alexander-Universität Erlangen-Nürnberg, 90762 Fürth, Germany. Electronic address:
Extrusion-based 3D bioprinting is one of the most promising and widely used technologies in bioprinting. However, the development of bioprintable, biocompatible bioinks with tailored mechanical and biological properties remains a major challenge in this field. Alginate dialdehyde-gelatin (ADA-GEL) hydrogels face these difficulties and enable to tune the mechanical properties depending on the degree of oxidation (% DO) of ADA.
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