Two new coumarin glycosides, praerosides VI (1) and VII (2), were isolated from the roots of Peucedanum praeruptorum Dunn. Their structures were elucidated by chemical reaction and NMR spectroscopic methods.
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http://dx.doi.org/10.1080/10286020801966740 | DOI Listing |
J Pharm Biomed Anal
December 2024
State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China; Institute of Collaborative Innovation in Great Health, College of Biotechnology and Food Science, Tianjin Key Laboratory of Food Biotechnology, Tianjin University of Commerce, Tianjin 300134, China. Electronic address:
Huo-Xiang-Zheng-Qi Mixture is a renowned traditional Chinese medicine formula used to treat ailments associated with dampness pathogens. This study employed ultra-high-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry to perform a comprehensive qualitative and quantitative analysis of the chemical compounds in Huo-Xiang-Zheng-Qi Mixture. A total of 155 compounds were identified, including 61 flavonoids and their glycosides, 36 phenylethanoid glycosides, 23 saponins, 14 coumarins, 9 organic acids, 1 amino acid, 2 nucleosides and purines, and 9 additional compounds.
View Article and Find Full Text PDFMolecules
December 2024
School of Pharmacy and Pharmaceutical Sciences, Panoz Institute, and Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, D02 PN40 Dublin, Ireland.
is a lesser-known plant species belonging to the genus that grows in Kazakhstan. The aim of this study was to characterize the composition of the ethanolic, water, and hydroethanolic extracts from the aerial parts of by HPLC-ESI-QTOF-MS/MS to isolate the major compound isoquercitrin by HSCCC (High-Speed Counter-Current Chromatography) and to determine the cytotoxicity and anti-inflammatory potential of the extracts produced with this plant. Fingerprinting of the analyzed extracts showed the presence of a multitude of metabolites comprising polyphenols, organic acids, and coumarins, and only trace quantities of cardiac glycosides in the analyzed samples.
View Article and Find Full Text PDFAm J Transl Res
November 2024
Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional Ciudad de México, México.
The L. genus, belonging to the Moraceae family, includes around 850 species that are widely distributed in tropical and subtropical regions around the world; including the Eastern Mediterranean, Asia, Africa, Australia, and a large territory of America. Among the most important species are , , , , , Vahl, , , , and .
View Article and Find Full Text PDFFungal Biol
December 2024
Université de Lorraine, INRAE, IAM, F-54000, Nancy, France. Electronic address:
Plant metabolites have a great potential for limiting the spread of harmful fungi. However, a better understanding of the mode-of-action of these molecules and the defense systems developed by fungi to resist them, is needed to assess the benefits/risks of using them as antifungal treatment. White-rot fungi are excellent models in this respect, as they have adapted to the hostile habitat that is wood.
View Article and Find Full Text PDFJ Sep Sci
December 2024
School of Pharmaceutical Science and Technology, Faculty of Medicine, Tianjin University, Tianjin, China.
Shenfu Qiangxin (SFQX) pills are proprietary traditional Chinese medicine used for the treatment of chronic heart failure with significant clinical effects. However, the systematic identification and quantification of complexed components in SFQX have not been reported yet. In this work, a reliable and comprehensive method for a rapid identification of chemical components was developed by data dependent acquisition using ultra performance liquid chromatography coupled with high-resolution mass spectrometry (UHPLC-Q Exactive-Orbitrap-MS).
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