[Vascular architecture of the skin in the postmortem microangiogram].

Rofo

Klinik für Radiologische Diagnostik, RWTH Aachen.

Published: January 1991

To demonstrate the detailed vascular architecture of the skin, barium sulphate suspension was injected into the arteries of nine amputated lower limbs. Sections of skin from the foot were fixed in formalin and embedded in paraffin and then examined by high resolution radiography. Subsequently histological sections were prepared and correlated with the micro-angiographic appearances. This technique provided demonstration of the detailed vascular structure of the skin with very little super imposition. The capillary loops in the papillae, the sub-papillary plexus, the glandular components (with the capillaries surrounding the sweat glands), the fine arteries and smallest veins in the cutis could be demonstrated over a prolonged course. Microangiographic and histologic sections were carried out in parallel. These eliminated artifacts and clarified the micro-angiographic appearances. The value of microangiography for demonstrating the vascularity of the skin under normal, pathological and experimental conditions is the subject of further studies.

Download full-text PDF

Source
http://dx.doi.org/10.1055/s-2008-1033076DOI Listing

Publication Analysis

Top Keywords

architecture skin
8
detailed vascular
8
micro-angiographic appearances
8
skin
5
[vascular architecture
4
skin postmortem
4
postmortem microangiogram]
4
microangiogram] demonstrate
4
demonstrate detailed
4
vascular architecture
4

Similar Publications

Self-rerouting sensor network for electronic skin resilient to severe damage.

Nat Commun

January 2025

Toyota Central R&D Labs. Inc.; 41-1, Yokomichi, Nagakute, Aichi, Japan.

We propose a network architecture for electronic skin with an extensive sensor array-crucial for enabling robots to perceive their environment and interact effectively with humans. Fault tolerance is essential for electronic skins on robot exteriors. Although self-healing electronic skins targeting minor damages are studied using material-based approaches, substantial damages such as severe cuts necessitate re-establishing communication pathways, traditionally performed with high-functionality microprocessor sensor nodes.

View Article and Find Full Text PDF

A high-resolution view of the immune and stromal cell response to infection in human volunteers.

mBio

January 2025

Department of Medical and Molecular Genetics and Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, Indiana, USA.

causes the genital ulcer disease chancroid and cutaneous ulcers in children. To study its pathogenesis, we developed a human challenge model in which we infect the skin on the upper arm of human volunteers with to the pustular stage of disease. The model has been used to define lesional architecture, describe the immune infiltrate into the infected sites using flow cytometry, and explore the molecular basis of the immune response using bulk RNA-seq.

View Article and Find Full Text PDF

Research has proved a close relationship between environments and physiological as well as psychological responses. However, existing research based on neuroscience experiments demonstrated a clear dichotomy between natural and built environments in the selection of exposure settings. There is very limited research analyzing and comparing the effects of different urban environments on individual psychological health.

View Article and Find Full Text PDF

Fetal fibroblast heterogeneity defines dermal architecture during human embryonic skin development.

J Invest Dermatol

January 2025

Centre for Gene Therapy and Regenerative Medicine, King's College London, Guy's Hospital, Great Maze Pond, London, UK; Directors' Unit, EMBL, Meyerhofstr. 1, 69117 Heidelberg, Germany. Electronic address: https://twitter.com/fionamarywatt.

To investigate heterogeneity of fibroblasts in human fetal skin, we analysed published single-cell RNA sequencing data (8 and 16 post conception weeks (PCW)) and performed single-molecule fluorescence in situ hybridisation to map their spatial distribution and predicted dynamic interactions. Clustering revealed 8 fibroblast populations with developmental stage-specific abundance changes. Proliferative cells (MKI67+) were present at all stages.

View Article and Find Full Text PDF

Sphingolipids serve as building blocks of membranes to ensure subcellular compartmentalization and facilitate intercellular communication. How cell type-specific lipid compositions are achieved and what is their functional significance in tissue morphogenesis and maintenance has remained unclear. Here, we identify a stem cell-specific role for ceramide synthase 4 (CerS4) in orchestrating fate decisions in skin epidermis.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!