AI Article Synopsis

  • Up to 50% of methicillin-susceptible Staphylococcus aureus (MSSA) bloodstream isolates in a hospital from 1999 to 2006 shared genetic similarities with prevalent methicillin-resistant S. aureus (MRSA) strains.
  • Several successful MSSA lineages, including clonal complex 7 (CC7) and clonal complex 15 (CC15), were also identified during this period.
  • The findings highlight the genetic overlap between MSSA and MRSA, indicating potential challenges in managing these infections.

Article Abstract

We observed that, between 1999 and 2006, up to 50% of the methicillin-susceptible Staphylococcus aureus (MSSA) bloodstream isolates in our hospital had a genetic background common to endemic methicillin-resistant S. aureus clones (clonal complex 5 [CC5], CC8, CC22, CC30, and CC45). Furthermore, several successful MSSA lineages, such as CC7 and CC15, were observed.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2446898PMC
http://dx.doi.org/10.1128/JCM.00808-08DOI Listing

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