Gene variant intron C G-42A of protein Z is significantly associated with the occurrence of fetal loss. A previously unreported sporadic missense mutation within exon 8 is described in a patient with very low protein Z levels.
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http://dx.doi.org/10.1016/j.fertnstert.2007.07.1318 | DOI Listing |
Sci Rep
December 2024
School of Civil and Hydraulic Engineering, Ningxia University, Yinchuan, Ningxia, 750021, China.
Lycium barbarum is an important economic crop in the arid region of Northwest China, and the regulation of irrigation and fertilisation is an important way to improve the quality and yield of Lycium barbarum. To explore the effects of water-fertiliser coupling on photosynthesis, quality and yield of Lycium barbarum under irrigation methods based on predicted crop evapotranspiration (ET), ET was calculated via reference evapotranspiration (ET) predicted on the basis of public weather forecasts, and the irrigation water volume was determined as a proportion of this ET. A field experiment was conducted via a completely randomised experimental design with five irrigation water volumes (W0 (100% ET), W1 (90% ET), W2 (80% ET), W3 (70% ET) and W4 (65% ET)) and three fertiliser application rates (high fertiliser (FH), medium fertiliser (FM) and low fertiliser (FL)).
View Article and Find Full Text PDFCommun Biol
December 2024
Fujian Key Laboratory of Translational Research in Cancer and Neurodegenerative Diseases, Institute for Basic Medical Sciences, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China.
High-fat diet (HFD) induces low-grade chronic inflammation, contributing to obesity and insulin resistance. However, the precise mechanisms triggering obesity-associated metabolic inflammation remain elusive. In this study, we identified epigenetic factor Brd4 as a key player in this process by regulating the expression of Ccr2/Ccr5 in colonic macrophage.
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December 2024
Department of Pathology, Faculty of Veterinary, Atatürk University, Erzurum, Turkey.
Oxidative stress and inflammation are indispensable components of ischemia-reperfusion (IR) injury. In this study, we investigated the effects of low and high doses of caftaric acid (CA) on reducing kidney and remote organ damage induced by IR. We divided Wistar rats into four groups: sham, IR, low (40 mg/kg body weight (BW)), and high (80 mg/kg BW) CA groups.
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December 2024
Department of Pathology, Kitasato University School of Medicine, 1-15-1 Kitasato, Minami-ku, Sagamihara, 252-0374, Kanagawa, Japan.
To investigate the functional role of S100A4 in advanced colorectal carcinoma (Ad-CRC) and locally advanced rectal carcinoma (LAd-RC) receiving neoadjuvant chemoradiotherapy (NCRT). We analyzed histopathological and immunohistochemical sections from 150 patients with Ad-CRC and 177 LAd-RC patients treated with NCRT. S100A4 knockout (KO) HCT116 cells were also used.
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December 2024
Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.
PrPc is expressed in various tumors and is associated with cancer progression, but previous studies have shown conflicting results regarding its relationship with patient prognosis-potentially due to differences in the antibodies used. This study aimed to clarify the relationship between PrPc expression and primary esophageal squamous cell carcinoma (ESCC) and primary hepatocellular carcinoma (HCC) using a novel anti-PrPc antibody, 4AA-m, noted for its high specificity and sensitivity. We used flow cytometry to detect PrPc expression in ESCC and HCC cell lines.
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