We conducted a randomized, double-blind, placebo-controlled trial comparing supplementation with bovine lactoferrin versus placebo for the prevention of diarrhea in children. Comparison of overall diarrhea incidence and prevalence rates found no significant difference between the 2 groups. However, there was a lower prevalence of colonization with Giardia species and better growth among children in the lactoferrin group.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2440650 | PMC |
| http://dx.doi.org/10.1086/588476 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Lactoferrin-modified nanoemulsions enhance brain-targeting and therapeutic efficacy of arctigenin against Toxoplasma gondii-induced neuronal injury.
Int J Parasitol Drugs Drug Resist
December 2024
Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, Molecular Medicine Research Center, College of Pharmacy, Yanbian University, Yanji, 133002, Jilin Province, China. Electronic address:
Toxoplasma gondii, a neurotropic protozoan parasite, affects the central nervous system and causes various neurological disorders. Previous studies have demonstrated that Arctigenin (AG) exhibits anti-T. gondii activity and reduces depression-like behaviors induced by T.
View Article and Find Full Text PDFCamel milk extracellular vesicles/exosomes: a fascinating frontier in isolation and therapeutic potential.
Food Funct
December 2024
Department of Anatomy & Embryology, Faculty of Veterinary Medicine, Kafrelsheikh University, Egypt.
Camel milk has a unique composition that sets it apart from other types of animal milk, which has captured the interest of medical and scientific communities. Extracellular vesicles (EVs) mainly contain exosomes (Exos, 30-200 nm) and microvesicles (MVs, 200-1000 nm). Camel milk EVs, particularly Exos, which we named EVs/Exos, have arisen as a fascinating area of scientific inquiry, holding enormous potential for the future of biomedicine due to their anticancer, antibacterial, antidiabetic nephropathy, and immunostimulatory impacts.
View Article and Find Full Text PDFProteomics and surface free fatty acid analysis of milk fat globule in the spray- and freeze-dried bovine, goat and horse milk powders.
J Dairy Sci
December 2024
College of Food Science and Engineering, Qingdao Agricultural University, Qingdao 266109, Shandong, China. Electronic address:
Changes in the structure and composition of milk fat globules in spray- and freeze-dried milk powders have recently garnered significant attention. This study investigated changes in milk fat globular membrane (MFGM) proteins from bovine, goat, and horse milk powders, both spray- and freeze-dried, using a label-free proteomics approach, and quantified surface free fatty acids and their composition using gas chromatography. The results showed that several proteins of α-casein and β-lactoglobulin increased, while fibrinogen α, β chain, and mucin-1 decreased in the MFGM fractions of the studied spray-dried milk powders.
View Article and Find Full Text PDFEffects of Forming Lactoferrin-Milk Protein Complexes on Lactoferrin Functionality and Intestinal Development in Infancy.
Nutrients
November 2024
Department of Nutrition, University of California, Davis, CA 95616, USA.
Article Synopsis
- Lactoferrin (Lf) can form protein complexes with α-lactalbumin (α-Lac) and proteins from whey protein hydrolysate (WPH) and nonfat milk powder (MP), which may influence its effects on human intestinal cells.
- Complexed Lf demonstrates increased resistance to digestion compared to Lf alone, but maintains its ability to bind to receptors and be absorbed by intestinal cells.
- Despite forming complexes with other proteins, Lf retains its biological activities, such as promoting cell growth and differentiation, enhancing immune responses, and inhibiting harmful bacteria.
Role of maternal milk in providing a healthy intestinal microbiome for the preterm neonate.
Pediatr Res
December 2024
Health Sciences Post-graduate Program, FAMED, UFU, Uberlandia, MG, Brazil.
The immature gastrointestinal tract of preterm neonates leads to a delayed and distinctive establishment of the gut microbiome, making them susceptible to potentially pathogenic bacteria and increasing the risk of infections. Maternal milk, recognized as the optimal source of nutrition, plays a multifaceted role in modulating the gut microbiome of premature newborns. Human milk oligosaccharides, acting as prebiotics, provide essential nourishment for key bacteria such as Bifidobacterium, contributing to the proliferation of beneficial bacterial populations.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!