Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1038/nsmb0508-432 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Comprehensive analysis of bioinformatics and system biology reveals the association between Girdin and hepatocellular carcinoma.
PLoS One
December 2024
Center of Infectious Diseases, West China Hospital, Sichuan University, Chengdu, China.
Introduction: Hepatocellular carcinoma is one of the leading causes of cancer-related mortality worldwide. The actin-binding protein Girdin is overexpressed in various tumors, promoting tumorigenesis and progression. However, the exact mechanisms by which Girdin regulates liver cancer remain poorly understood.
View Article and Find Full Text PDFQuantitative proteomic profiling reveals sexual dimorphism in the retina and RPE of C57BL6 mice.
Biol Sex Differ
October 2024
Department of Ophthalmic Research, Cole Eye Institute, Cleveland Clinic, Cleveland, OH, USA.
Article Synopsis
- * A study used quantitative proteomics (iTRAQ) to analyze protein expression in the retinas and retinal pigment epithelium (RPE) of male and female mice, identifying significant differences.
- * The findings highlighted distinct pathways activated in male and female tissues, suggesting that these differences could influence the development and progression of retinal diseases.
Sodium Fluoride Exposure Induces Developmental Toxicity and Cardiotoxicity in Zebrafish Embryos.
Biol Trace Elem Res
September 2024
Clinical Research Center, The First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine, No. 71 Bao Shan North Road, Yunyan District, Guiyang, 550001, Guizhou Province, China.
Article Synopsis
- Fluorosis poses a global health risk, affecting heart development in embryos, and this study specifically investigated the toxic effects of sodium fluoride (NaF) on zebrafish embryos.
- Key findings included a 50% lethal concentration of NaF at 335.75 mg/L, significant deformities in embryos at concentrations above 200 mg/L, and a dose-dependent reduction in heart rate and cardiac function.
- High-throughput RNA sequencing revealed 1354 differentially expressed genes linked to heart development in NaF-treated embryos, activating pathways related to cardiac function and malformation, thus uncovering the mechanisms behind fluoride-induced heart abnormalities.
Comparative analysis of testicular fusion in Spodoptera litura (cutworm) and Bombyx mori (silkworm): Histological and transcriptomic insights.
Gen Comp Endocrinol
September 2024
Guangdong Provincial Key Laboratory of Insect Developmental Biology and Applied Technology, Guangzhou Key Laboratory of Insect Development Regulation and Application Research, Institute of Insect Science and Technology, School of Life Sciences, South China Normal University, Guangzhou 510631, China. Electronic address:
Spodoptera litura commonly known as the cutworm, is among the most destructive lepidopteran pests affecting over 120 plants species. The powerful destructive nature of this lepidopteran is attributable to its high reproductive capacity. The testicular fusion that occurs during metamorphosis from larvae to pupa in S.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!