AI Article Synopsis
- Osteolytic metastases around the acetabulum can cause severe pain and structural issues in cancer patients, leading to a poor quality of life, and percutaneous acetabuloplasty is a mini-invasive procedure to manage these lesions, especially for those unfit for major surgery or ineffective radiotherapy.
- A study with 25 patients evaluated pain and mobility before and after the procedure using various assessment tools; results showed significant improvements in pain relief and quality of life during the first six months post-operation.
- While 59% of patients achieved complete pain relief and 41% reported pain reduction, the positive effects were mostly temporary and worsened after six months, indicating that percutaneous acetabuloplasty can aid other treatments for managing pain in patients
Article Abstract
Background: Osteolytic metastases around the acetabulum are frequent in tumour patients, and may cause intense and drug-resistant pain of the hip. These lesions also cause structural weakening of the pelvis, limping, and poor quality of life. Percutaneous acetabuloplasty is a mini-invasive procedure for the management of metastatic lesions due to carcinoma of the acetabulum performed in patients who cannot tolerate major surgery, or in patients towards whom radiotherapy had already proved ineffective.
Methods: We report a retrospective study in 25 such patients (30 acetabuli) who were evaluated before and after percutaneous acetabuloplasty, with regard to pain, mobility of the hip joint, use of analgesics, by means of evaluation forms: Visual Analog Scale, Harris Hip Score, Western Ontario and McMaster Universities Index of Osteoarthritis (WOMAC), Eastern Cooperative Oncology Group (ECOG). The results obtained were analysed using the chi2 Test and Fisher's exact test. Significance was sent at P < 0.05.
Results: Marked clinical improvement was observed in all patients during the first six post-operative months, with gradual a worsening thereafter from deterioration of their general condition. Complete pain relief was achieved in 15 of our 25 (59%) of patients, and pain reduction was achieved in the remaining 10 (41%) patients. The mean duration of pain relief was 7.3 months. Pain recurred in three patients (12%) between 2 weeks to 3 months. No major complications occurred. There was transient local pain in most cases, and 2 cases of venous injection of cement without clinical consequences.
Conclusion: Percutaneous acetabuloplasty is effective in improving the quality of life of patients with osteolytic bone tumours, even though the improvement is observed during the first 6 months only. It can be an effective aid to chemo- and radiotherapy in the management of acetabular metastases.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2390555 | PMC |
| http://dx.doi.org/10.1186/1471-2474-9-66 | DOI Listing |
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