Wistar rats were implanted subcutaneously with 2.5 x 6 mm cylindrical matrices, made from the home-made metacrylate material Akpol S, and, for comparative purposes, with the imported materials Trevalon and Superacryl. At different time intervals quantitative and qualitative analyses of the picture of leucocytes and of blood plasma proteins were carried out in groups of animals implanted with the above-mentioned materials and in a control one. No differences in the values of the above parameters were found in any of the examined groups of animals. The carried out tests were aimed at making a thorough study of general reaction of the living organism to the new, home-made metacrylate material Akpol S, used for making removable dentures.
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