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Physical violence and its associations: Insights from nationally representative data in India.
Womens Health (Lond)
January 2025
Global Health, and Department Pediatrics, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Background: Empowerment is vital for individuals' control over their lives but is often constrained for women in India due to deep-rooted patriarchal norms. This affects health, and resource distribution, and increases domestic violence. Domestic violence including physical, sexual, emotional, economic, and psychological abuse is a significant human rights and public health issue.
View Article and Find Full Text PDFOverexpression of TRPV6 Inhibits Coronary Atherosclerosis-Related Inflammatory Response and Cell Apoptosis via the PKA/UCP2 Pathway.
Cardiovasc Ther
January 2025
Department of Cardiovascular Medicine, Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Taiyuan, Shanxi Province 030032, China.
This research is aimed at unravelling the intricate relationship between transient receptor potential vanilloid 6 (TRPV6), protein kinase A (PKA), uncoupling protein 2 (UCP2), and atherosclerosis. By shedding light on the role of the TRPV6/PKA/UCP2 pathway in inhibiting inflammatory response and cell apoptosis in coronary atherosclerotic plaques, this study provides valuable insights into potential therapeutic targets for treating coronary artery disease (CAD). We established animal and cell models of atherosclerosis.
View Article and Find Full Text PDFUnraveling Alzheimer's disease: insights from single-cell sequencing and spatial transcriptomic.
Front Neurol
December 2024
The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, Zhejiang, China.
Article Synopsis
- Alzheimer's disease (AD) is a progressive condition that leads to cognitive decline, with a focus on memory and executive functions.
- Recent advancements in single-cell sequencing and spatial transcriptomics help uncover the complex cellular interactions involved in AD, highlighting distinct cell types that drive neuroinflammation and degeneration.
- The integration of these advanced technologies is essential for developing targeted therapies and personalization in medicine, emphasizing the importance of collaboration across disciplines to improve treatments and patient care.
Deployment of Industry 4.0 technologies to achieve a circular economy in agri-food supply chains: A thorough analysis of enablers.
J Environ Manage
December 2024
School of Economics and Management, Fuzhou University, Fuzhou, China. Electronic address:
With the global population projected to reach 9.7 billion by 2050, pressure on global natural resources will increase by 50-90%, exceeding planetary boundaries. Industry 4.
View Article and Find Full Text PDFHow investment in children shape fertility choices of families: Evidence from Pakistan.
PLOS Glob Public Health
December 2024
Research and Development Solutions, Islamabad, Pakistan.
Fertility patterns are transitioning globally in that couples are choosing to have fewer children as they become more affluent, and parents are investing more time and resources in the lives of their children than they can receive back. This change is more established in developed countries and is now being recognized in developing countries. We explored this phenomenon and its implications for family planning in Pakistan, hypothesizing a quantity-quality transition underway.
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