We report our experience about intraepithelial squamous carcinoma of the vulva, consisting of 20 cases with clinical and histopathological diagnosis, at the University of Chile Clinical Hospital. Between december 1972 and october 1989. The age of patients was between 30 and 78 years old, median age 57.6 years old. Clinical HPV infection was detected in three cases (15%) 17 patients were submitted to simple total, vulvectomy (94.5%) without operatory mortality. The follow-up was between 3 months and 11 years (mean follow-up 6.5 years). Recurrence was observed in 2 patients (11.1%) of the 18 submitted to treatment.
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Int J Gynecol Cancer
January 2025
Hacettepe University, Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Faculty of Medicine, Ankara, Turkey.
Background: Vulvar squamous cell carcinoma incidence is increasing, especially among women under 60, largely attributed to human papillomavirus infections. Precursor pre-invasive vulvar lesions are frequently underdiagnosed. Routine vulvar inspection during cervical cancer screening could offer an opportunity for the detection of these lesions.
View Article and Find Full Text PDFCurr Oncol
December 2024
Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Vulvar cancer is one of the rarest gynecological malignancies. The development of this condition can be associated with either dysplasia linked to human papillomavirus (HPV), primarily affecting younger women, or vulvar dermatoses such as lichen sclerosus, which predominantly affect older women. Over the last decade, the incidence of vulvar cancer has risen by 0.
View Article and Find Full Text PDFAm J Dermatopathol
February 2025
Departments of Dermatology and Pathology, School of Medicine, Wake Forest University, Medical Center BLVD, Winston Salem, NC.
Primary vulvar carcinomas are rare and constitute a diverse group of neoplasms. These primary tumors are typically classified based on their presumed tissue of origin or histological characteristics. Among these, carcinomas of sweat gland origin are particularly significant.
View Article and Find Full Text PDFGynecol Oncol Rep
February 2025
People's Hospital of China Medical University, Department of Gynecology, People's Hospital of Liaoning Province, Shenyang, China.
Background: Keratoacanthoma is a relatively rare skin tumor, with vulvar keratoacanthoma being even more uncommon. Although the majority of keratoacanthomas exhibit a benign course, a subset of cases may show features of malignant potential, such as marginal invasion and recurrence.
Case: An 82-year-old female presented with a rapidly growing exophytic lesion on the left vulva, measuring 1.
Ecancermedicalscience
October 2024
Facultad de Medicina, Universidad Privada Antenor Orrego, Trujillo 13008, Perú.
Basal cell carcinoma (BCC) is the most common non-melanoma type of skin cancer described in humans that originates in the epidermis, more specifically in the basal layer and its appendages. Environmental, genetic and phenotypic factors contribute to the onset of this cancer; however, damage caused by ultraviolet radiation from sunlight is the primary risk factor. The emergence of this neoplasm in unexposed body areas, such as the soles, groin, armpit, scrotum or vulva is very rare.
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