The synergy of the activities between chloroquine and various human immunodeficiency virus protease inhibitors was investigated in chloroquine-resistant and -sensitive malaria parasites. In both in vitro and in vivo assay systems, ritonavir was found to be the most potent in potentiating the antimalarial action of chloroquine.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2443913PMC
http://dx.doi.org/10.1128/AAC.01329-07DOI Listing

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