A comprehensive experimental, analytical and numerical study of the true focal region drift relative to the geometrical focus (focal shift effect) in acoustic focused beams and its nonlinear evolution is presented. For this aim, the concept of Fresnel number, proportional to the linear gain, is introduced as a convenient parameter for characterizing focused sources. It is shown that the magnitude of the shift is strongly dependent on the Fresnel number of the source, being larger for weakly focused systems where a large initial shift occurs. Analytical expressions for axial pressure distributions in linear regime are presented for the general case of truncated Gaussian beams. The main new contribution of this work is the examination of the connection between the linear and nonlinear stages of the focal shift effect, and its use for the estimation of the more complicated nonlinear stage. Experiments were carried out using a continuous-wave ultrasonic beam in water, radiated by a focused source with nominal frequency f=1 MHz, aperture radius a=1.5 cm and geometrical focal distance R=11.7 cm, corresponding to a Fresnel number N(F)=1.28. The maximum measured shifts for peak pressure and intensity were 4.4 and 1.1cm, respectively. The evolution of the different maxima with the source amplitude, and the disparity in their axial positions, is interpreted in terms of the dynamics of the nonlinear distortion process. Analytical results for the particular case of a sound beam with initial Gaussian distribution are also presented, demonstrating that the motion of peak pressure and peak intensity may occur in opposite directions.
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J Cannabis Res
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Laboratori de Botànica (UB), Facultat de Farmàcia i Ciències de l'Alimentació-Institut de Recerca de la Biodiversitat (IRBio), Unitat Associada al CSIC, Universitat de Barcelona, Av. Joan XXIII 27-31, Barcelona, Catalonia, 08028, Spain.
Background: Cannabis sativa L. (Cannabaceae) has been widely used by humans throughout its history for a variety of purposes (medicinal, alimentary and other uses). Armenia, with its rich cultural history and diverse ecosystems, offers a unique context for ethnobotanical research about traditional uses of Cannabis.
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Training and Sports Sciences, University of Applied Sciences Wiener Neustadt, Johannes Gutenberg-Straße 3, Wiener Neustadt, 2700, Austria.
Background: Isokinetic dynamometry is a common tool for evaluating muscle function and is used across various disciplines. Technical advancements have shifted focus towards multi-joint exercises such as the leg press, offering insights into practical human movement dynamics. However, previous reproducibility studies have focused predominantly on single-joint exercises, warranting investigations into the reliability of multi-joint exercises.
View Article and Find Full Text PDFBMC Vet Res
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Department of Large Animal Diseases and Clinic, Institute of Veterinary Medicine, Warsaw University of Life Sciences, Warsaw, 02-787, Poland.
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View Article and Find Full Text PDFJ Subst Use Addict Treat
January 2025
Department of Public Health and Community Medicine, Tufts University School of Medicine, Boston, MA 02111, United States of America.
Introduction: The location of buprenorphine treatment providers in the United States is pivotal to the understanding of regional factors associated with prescription and uptake. We evaluated how distinct data sources of treatment providers and their associated locations contribute to the differences observed when measuring buprenorphine accessibility.
Methods: We compared buprenorphine treatment provider data from the Drug Enforcement Administration (DEA) and data from the behavioral health treatment locator from the Substance Abuse and Mental Health Services Administration (SAMHSA) for July 2022.
J Biol Chem
January 2025
Department of Biomedical Science, Faculty of Health and Society, Malmö University, SE-205 06 Malmö, Sweden. Electronic address:
Apolipoprotein E (APOE) is distributed across various human tissues and plays a crucial role in lipid metabolism. Recent investigations have uncovered an additional facet of APOE's functionality, revealing its role in host defense against bacterial infections. To assess the antibacterial attributes of APOE3 and APOE4, we conducted antibacterial assays using P.
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