Primary cutaneous aspergillosis in a patient with a solid organ transplant: case report and review of the literature.

Cutis

Department of Dermatology, Vanderbilt University Medical Center, The Vanderbilt Clinic, Nashville, TN 37232, USA.

Published: February 2008

Goal: To understand primary cutaneous aspergillosis to better manage patients with the condition.

Objectives: Upon completion of this activity, dermatologists and general practitioners should be able to: 1. Describe risk factors for Aspergillus infection. 2. Identify diagnostic methods for primary cutaneous aspergillosis. 3. Discuss treatment options for primary cutaneous aspergillosis. Primary cutaneous aspergillosis is an uncommon disease in immunocompetent individuals that often affects immunosuppressed hosts. We present the first reported case of primary cutaneous aspergillosis in a solid organ transplant recipient caused by Aspergillus niger. Fruiting bodies were isolated from a necrotic ulcer arising in a surgical wound. Debridement alone failed to resolve the infection, emphasizing the need for early antifungal treatment combined with surgical management of this infection.

Download full-text PDF

Source

Publication Analysis

Top Keywords

primary cutaneous
24
cutaneous aspergillosis
24
solid organ
8
organ transplant
8
primary
6
aspergillosis
6
cutaneous
5
aspergillosis patient
4
patient solid
4
transplant case
4

Similar Publications

Molecular Tracking of in an Archived Spleen Sample in Iran: A Case Report.

Iran J Parasitol

January 2024

Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

Rodents are the primary reservoir hosts for zoonotic cutaneous leishmaniasis (ZCL) caused by . Knowing reservoir hosts is crucial for leishmaniasis surveillance and control programs in endemic areas. In this study, we examined an archived spleen of obtained during a pest control program in 2000 in Tehran, the capital of Iran.

View Article and Find Full Text PDF

Point mutations at codon 600 of the BRAF oncogene are the most common alterations in cutaneous melanoma (CM). Assessment of BRAF status allows to personalize patient management, though the affordability of molecular testing is limited in some countries. This study aimed to develop a model for predicting alteration in BRAF based on routinely available clinical and histological data.

View Article and Find Full Text PDF

Background: Cutaneous melanoma is one of the most invasive and lethal skin malignant tumors. Compared to primary melanoma, metastatic melanoma (MM) presents poorer treatment outcomes and a higher mortality rate. The tumor microenvironment (TME) plays a critical role in MM progression and immunotherapy resistance.

View Article and Find Full Text PDF

The incidence of melanoma is increasing globally. The estimated worldwide incidence is projected to increase from 324,635 cases in 2020 to 510,000 in 2040. In the UK, melanoma accounts for 4% of all new cases of cancer.

View Article and Find Full Text PDF

Infantile hemangiomas (IH) are the most common benign tumors of infancy and progress through recognized stages of evolution including early proliferation, plateau, and involution. Ulceration is a common complication of IHs typically observed during the early proliferative stage characterized by rapid growth. In rare cases, ulceration is the primary clinical manifestation of IHs.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!