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Coupling of activated esters to gramines in the presence of ethyl propiolate under mild conditions. | LitMetric
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Coupling of activated esters to gramines in the presence of ethyl propiolate under mild conditions.

David T Jones Gerald D Artman Robert M Williams

Tetrahedron Lett

Department of Chemistry, Colorado State University, Fort Collins, CO 80523, USA University of Colorado Cancer Center, Aurora, CO 80045.

Published: February 2007

The coupling of activated esters to gramine derivatives is described using ethyl propiolate. A series of substrates have been prepared using these mild conditions to provide a scope and limitations for this methodology.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2346430PMC
http://dx.doi.org/10.1016/j.tetlet.2006.12.016DOI Listing

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