An apparent natural introduction and establishment of a population of Anopheles walkeri into an ecological research site is documented. Likelihood of introduction by human activity is discussed.
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http://dx.doi.org/10.2987/5600.1 | DOI Listing |
Drug Res (Stuttg)
January 2025
Ratnam Institute of Pharmacy, Nellore, Andhra Pradesh, India.
One of the most widespread arboviral diseases in the world, dengue virus disease (DVD) is primarily found in tropical and subtropical regions, affecting 129 countries. The main way that the dengue virus (DENV) spreads is through the bite of a female mosquito. Symptomatic therapy and supportive care are the primary methods of managing patients with DENV infection as there is currently no approved antiviral medication for this condition.
View Article and Find Full Text PDFMol Divers
January 2025
Department of Biosciences, Faculty of Science, Universiti Teknologi Malaysia, 81310, Johor Bahru, Johor, Malaysia.
Dengue is one of the most prevalent viruses transmitted by the Aedes aegypti mosquitoes. Currently, no specific medication is available to treat dengue diseases. The NS2B-NS3 protease is vital during post-translational processing, which is a key target in this study.
View Article and Find Full Text PDFZhongguo Xue Xi Chong Bing Fang Zhi Za Zhi
December 2024
Lixiahe Institute of Agricultural Sciences in Jiangsu Province; National Experimental Station of Yangzhou for Agricultural Microbiology, Yangzhou, Jiangsu 225007, China.
Objective: To investigate the physiological characteristics of subspecies (Bti) with double mutations of and genes and to assess the activity of Bti against larvae of under different external factors, so as to provide the theoretical evidence for the use of engineered bacteria of Bti for effective mosquito control.
Methods: wild-type strain Bt-59 and Bt-59 strain with mutation [Bt-59 (Δ)] were cultured in nutrient broth media for 24 hours, and Bt-59 strains with mutation [Bt-59 (Δ)] and double mutations of and [Bt-59 (Δ)] were cultured in nutrient broth media for 48 hours. Then, 5 μL of culture media were transferred to glass sides, and cell morphology and mother cell lysis were observed under an optical microscope.
Parasit Vectors
January 2025
University Hospital Heidelberg, Medical Faculty, Centre for Infectious Diseases, Heidelberg University, Im Neuenheimer Feld 324, 69120, Heidelberg, Germany.
Background: Malaria remains a key contributor to mortality and morbidity across Africa, with the highest burden in children under 5. Insecticide-based vector control tools, which target the adult Anopheles mosquitoes, are the most efficacious tool in disease prevention. Due to the widespread use of these interventions, insecticide resistance to the most used classes of insecticides is now pervasive across Africa.
View Article and Find Full Text PDFMed Vet Entomol
January 2025
Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Mass ivermectin (IVM) treatment of livestock (MITL) is under consideration as a malaria control tool as IVM-treated livestock are lethal to blood-feeding Anopheles mosquitoes. MITL is routinely used as a prophylaxis in livestock to reduce the burden and transmission of helminth infections. Recently, there has been a shift in the veterinary IVM market in Southeast Asia wherein nearly all standard IVM formulations are now co-formulated with clorsulon (CLO).
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