The aim of the study was to assess the effect of chronic steroid inhalation therapy on the upper airways in patients with chronic obstructive pulmonary disease (COPD). 44 patients with a first time diagnosis of COPD were evaluated. 22 (11 males, 11 females) were treated with Beclomethasone (1 mg per day) for 6 months. 22 patients that were not treated made up the control group. All had a laryngological and phonic examination carried out, including stroboscopy of the vocal cords, bacteriological and mycological examination of the oral flora. Prior therapy in all patients abnormal findings were present. The six months therapy produced only further increase of hypo-tonus of the vocal cords, without significantly affecting the phonation time and voice pattern. An increase of voice hoarseness, fungal and bacteriological infections were not found.
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