A 364 yv strain sensitive to the toxic effect of benzo(a)pyrene (BP) was identified among 49 mutant strains of Drosophila simulans. Heterozygotes female 364 x male Turku obtained by crossing 364 yv species with those of wild BP-resistant Turku strain were more sensitive than female Turku x male 364 heterozygotes to both toxic and mutagenic effects of the carcinogen in the test of induction of somatic mosaicism with the yellow marker. Non-carcinogenic pyrene appeared weekly toxic and non-mutagenic. Possible mechanisms of 364 yv strain sensitivity to BP as well as vistas in application of the strain for monitoring genotoxic environmental pollution are discussed.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Gene model for the ortholog of in .
MicroPubl Biol
January 2025
The University of Alabama, Tuscaloosa, AL USA.
Gene model for the ortholog of glycogen synthase ( ) in the May 2017 (Princeton ASM75419v2/DsimGB2) Genome Assembly (GenBank Accession: GCA_000754195.3 ). This ortholog was characterized as part of a developing dataset to study the evolution of the Insulin/insulin-like growth factor signaling pathway (IIS) across the genus using the Genomics Education Partnership gene annotation protocol for Course-based Undergraduate Research Experiences.
View Article and Find Full Text PDFDouble trouble: two retrotransposons triggered a cascade of invasions in Drosophila species within the last 50 years.
Nat Commun
January 2025
Biological Sciences, North Dakota State University, Fargo, USA.
Horizontal transfer of genetic material in eukaryotes has rarely been documented over short evolutionary timescales. Here, we show that two retrotransposons, Shellder and Spoink, invaded the genomes of multiple species of the melanogaster subgroup within the last 50 years. Through horizontal transfer, Spoink spread in D.
View Article and Find Full Text PDFComparative Analysis of Bam and Bgcn Sequences and Predicted Protein Structural Evolution.
bioRxiv
December 2024
Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY, USA.
The protein encoded by the gene () plays an essential role in early gametogenesis by complexing with the gene product of () to promote germline stem cell daughter differentiation in males and females. Here, we compared the AlphaFold2 and AlphaFold Multimer predicted structures of Bam protein and the Bam:Bgcn protein complex between where is necessary in gametogenesis to that in , where it is not. Despite significant sequence divergence, we find very little evidence of significant structural differences in high confidence regions of the structures across the four species.
View Article and Find Full Text PDFGene model for the ortholog of in .
MicroPubl Biol
November 2024
Biological Sciences, The University of Alabama, Tuscaloosa, AL 35487.
Gene model for the ortholog of ( ) in the May 2017 (Princeton ASM75419v2/DsimGB2) Genome Assembly (GenBank Accession: GCA_000754195.3 ) of . This ortholog was characterized as part of a developing dataset to study the evolution of the Insulin/insulin-like growth factor signaling pathway (IIS) across the genus using the Genomics Education Partnership gene annotation protocol for Course-based Undergraduate Research Experiences.
View Article and Find Full Text PDFTwo major-effect loci influence interspecific mating in females of the sibling species, Drosophila simulans and D. sechellia.
G3 (Bethesda)
November 2024
Centre for Neural Circuits and Behaviour, Department of Physiology, Anatomy and Genetics, University of Oxford, Mansfield Road, Oxford OX1-3SR, UK.
Secondary contact between incompletely isolated species can produce a wide variety of outcomes. The vinegar flies Drosophila simulans and D. sechellia diverged on islands in the Indian Ocean and are currently separated by partial pre- and postzygotic barriers.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!