The number of aberrant metaphases was used to assess the influence of a highly active interferon inducer--ridostin, a two-spiral RNA, on spontaneous mutagenesis and that induced by an antitumor drug photrin. A new property of ridostin, viz. the antimutagenic effect, was established. The effect may be important for protection of cells from potent mutagens such as cytotoxic drugs used for cancer treatment.

Download full-text PDF

Source

Publication Analysis

Top Keywords

[the interferon
4
interferon inducer
4
inducer ridostin
4
ridostin photrin-induced
4
photrin-induced mutagenesis
4
mutagenesis bone
4
bone marrow
4
marrow cells
4
cells mice]
4
mice] number
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!