AI Article Synopsis
- A woman diagnosed with Wegener's granulomatosis (WG) experienced bilateral vision problems due to a central nervous system (CNS) lesion.
- The diagnosis was confirmed through MR imaging and a brain biopsy, revealing a necrotizing granulomatous lesion.
- Following high-dose oral corticosteroid treatment, both her symptoms and lab results improved significantly, leading to the complete regression of the CNS lesion, indicating that corticosteroids may be effective in treating WG with CNS involvement.
Article Abstract
We report a case of Wegener's granulomatosis (WG) with central nervous system (CNS) involvement in a woman who complained of bilateral visual disturbance. The intracranial necrotizing granulomatous lesion was confirmed by MR imaging and brain biopsy. After high-dose oral corticosteroid treatment, not only clinical manifestations but also laboratory tests improved. Moreover, the CNS lesion completely regressed. This suggests that high-dose corticosteroid alone might be effective in treating WG with CNS involvement.
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| http://dx.doi.org/10.1007/s10165-008-0070-z | DOI Listing |
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