A new class of low-toxicity mosquito repellents is synthesized from alpha- and beta-pinene in terpenoid compounds and preliminary biological tests show promising mosquito repellency. Statistical modeling is built using Codessa in order to reveal the quantitative relationship between the structure and the biological activity and to provide the guidance for further synthetic work.
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| http://dx.doi.org/10.1016/j.bmcl.2008.03.091 | DOI Listing |
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