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Pretreatment with gonadotropin-releasing hormone (GnRH) antagonists to prevent the flare-up effect of long-acting GnRH agonists: results of a pilot study. | LitMetric
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Pretreatment with gonadotropin-releasing hormone (GnRH) antagonists to prevent the flare-up effect of long-acting GnRH agonists: results of a pilot study.

Andreas Mueller Theodoros Maltaris Lothar Häberle Inge Hoffmann Matthias W Beckmann Ralf Dittrich

Fertil Steril

Department of Obstetrics and Gynecology, Erlangen University Hospital, Erlangen, Germany.

Published: February 2009

This study evaluated in vivo whether the flare-up effect of GnRH agonists can be suppressed through pretreatment with a GnRH antagonist. The classic flare-up effect caused by 3.8 mg goserelin acetate could not be suppressed through pretreatment using a single dosage of 3.24 mg cetrorelix acetate.

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http://dx.doi.org/10.1016/j.fertnstert.2007.11.066DOI Listing

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