Aim: The study was undertaken to investigate possible influence of alcoholism on the course and psychopathology of schizophrenia.
Method: A representative sample of 61 subjects was selected from schizophrenic patients with a history of alcohol dependence (dual diagnosis) registered in the period of 1997-2000. They were compared with 60 control patients with a single diagnosis of schizophrenia. In two groups, with the interview and clinical scales, the onset, course and psychopathology of schizophrenia were assessed.
Results: Male patients with schizophrenia and alcohol dependence had a later mean age at onset of mental illness, women--a higher rate of alcohol abuse in the family compared to the control groups. In men with dual diagnosis, the negative symptoms were less prominent. Women with schizophrenia and alcohol dependence reported more depressive symptomatology.
Introduction: Chronic alcohol exposure in humans and rodents causes tolerance to the analgesic effects of alcohol, and enhances pain sensitivity during alcohol withdrawal (i.e., hyperalgesia).
Background: Although alcohol consumption is considered one of the risk factors for delirium in intensive care unit (ICU) patients, quantitative research on the association between alcohol use disorder (AUD) and the development of delirium in the ICU remains relatively scarce.
Methods: This retrospective cohort study was conducted using the Medical Information Mart for Intensive Care-IV database, including all patients admitted to the ICU for the first time and underwent delirium assessment. Patients were divided into AUD and non-AUD groups, with the primary outcome being the occurrence of ICU delirium.
Ethylene glycol or one of its oxidation products are believed to serve as reducing agents in the shape-controlled synthesis of Ag nanocubes (NCs) by the polyol process. The identity of end-groups of polyvinylpyrrolidone (PVP) impacts shape control with alcohol and aldehyde moieties serving as a primary Ag reducing agent. We explored the role of PVP end-groups in the polyol process by measuring the dependence of particle number density of Ag NCs produced on the initial concentration(s) of Ag and PVP using small angle x-ray scattering and statistically large particle size distributions analyzed by scanning electron microscopy.
Methamphetamine (MA) dependence leads to severe physical and psychological issues. Current treatments, including psychosocial therapies and residential rehabilitation, face limitations such as high relapse rates, cost, and accessibility issues. As a result, there is an urgent need for novel approaches to treat MA dependence that are effective, affordable, and accessible to patients.
