Background: Ocular trauma is a significant problem in pediatric patients. The aim of this investigation was to evaluate the demographic, etiologic and prophylactic factors of pediatric ocular trauma in a tertiary center in northern Taiwan.
Methods: A retrospective review of medical charts of patients aged 15 years or younger who visited the emergency department of Chang Gung Memorial Hospital, Taoyuan for ocular trauma between July 2003 and June 2004 was undertaken.
Results: Of the 228 children in this study, ocular trauma occurred more frequently in boys than in girls (151:77 patients, p < 0.0001). Twenty-one patients (9.2%) presented with bilateral trauma. The most common ocular injury was closed globe injury (178 patients, 78.1%). The next most common ocular injuries were burns (35 patients, 15.4%), open globe injuries (8 patients, 3.5%) and orbital injuries (7 patients, 3.1%). Falling was the most common cause of ocular trauma in these children, followed by trauma caused by a fist or other part of the body. Sharp objects such as knives or scissors were the most common cause of open globe injuries. Visual impairment (visual acuity less than 20/50) occurred in three open globe injury patients.
Conclusions: Ocular trauma in children is associated with visual loss. Many of the cases were preventable. Public education, general awareness and aggressive primary management may be indicated to optimize visual outcome.
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Invest Ophthalmol Vis Sci
January 2025
Department of Ophthalmology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Purpose: Corneal alkali burns are severe ocular injuries characterized by intense inflammation, tissue damage, and vision impairment, with current treatments often insufficient in restoring corneal function and clarity. This study aimed to evaluate the therapeutic effects of recombinant thrombomodulin domain 1 (rTMD1) in the treatment of corneal alkali burns, focusing on its impact on inflammation, tissue repair, fibrosis, and neovascularization.
Methods: A murine model of corneal alkali burn was utilized to investigate the therapeutic potential of rTMD1.
Semin Ophthalmol
January 2025
Department of Ophthalmology and Visual Science, Rutgers New Jersey Medical School, Newark, NJ, USA.
Purpose: To characterize the epidemiology of consumer product-related ocular injury in the United States (US) incarcerated population, and identify preventable causes.
Methods: The National Electronic Injury Surveillance System (NEISS) database was queried for cases of eye injury from 2014 to 2023. Incarcerated cases were identified using the keywords "prison", "jail", "inmate", and "incarcerate".
Korean J Ophthalmol
January 2025
Department of Ophthalmology, Gil Medical Center, Incheon, Gachon University College of Medicine, Incheon, Korea.
Purpose: To analyze the frequency, and clinical characteristics of ocular injuries in patients with prior blow-out fractures who experience new blunt trauma, and to assess whether old orbital fractures provide a protective effect against subsequent ocular trauma.
Methods: The medical records of 1,315 ocular trauma patients were reviewed. A total of 927 patients who had orbital or facial CT scans and ophthalmologist evaluations were considered.
Surg Neurol Int
December 2024
Department of Surgery, Baghdad Teaching Hospital, Baghdad, Iraq.
Background: Orbital bullet injuries resulting from high-velocity trauma pose significant clinical challenges due to the potential for severe ocular and systemic complications. This meta-analysis consolidates the existing body of knowledge on direct orbital bullet injuries with respect to clinical outcomes, management strategies, and long-term effects.
Methods: The literature search was conducted by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses, using databases such as PubMed and Scopus.
Regen Biomater
November 2024
State Key Laboratory of Ophthalmology, Optometry and Vision Science, Wenzhou Medical University, Wenzhou, Zhejiang 325027, China.
Nerve injuries can be tantamount to severe impairment, standard treatment such as the use of autograft or surgery comes with complications and confers a shortened relief. The mechanism relevant to the regeneration of the optic nerve seems yet to be fully uncovered. The prevailing rate of vision loss as a result of direct or indirect insult on the optic nerve is alarming.
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