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Chlorhexidine Compared with Povidone-Iodine in Intravitreal Injection: A Systematic Review and Meta-Analysis.
J Ocul Pharmacol Ther
January 2025
Storm Eye Institute, Medical University of South Carolina, South Carolina, USA.
Povidone-iodine (PI) is the standard antiseptic for intravitreal injections (IVIs), while chlorhexidine (CHX) is a potential alternative. The efficacy of PI versus CHX in preventing endophthalmitis remains debated, with studies showing mixed results. To compare the effectiveness of using PI compared with CHX in IVI procedures regarding endophthalmitis rates, culture-positive endophthalmitis rates, and changes in visual acuity.
View Article and Find Full Text PDFGoniotomy for Childhood Glaucoma Secondary to Uveitis: Long-term Outcomes.
J Glaucoma
January 2025
Department of Ophthalmology and Visual Sciences, University of British Colombia, Vancouver, BC.
Precis: Goniotomy is effective in managing intraocular pressure in childhood glaucoma secondary to uveitis with cumulative probability of success 0.94 after 1 year and 0.77 after 5 years.
View Article and Find Full Text PDFA Case of Freeman-Sheldon Syndrome With Glaucoma Successfully Treated by Trabeculotomy Using the Kahook Dual Blade.
Cureus
December 2024
Department of Ophthalmology and Visual Science, Nagoya City University Graduate School of Medical Sciences, Nagoya, JPN.
This case study details a 41-year-old male patient with Freeman-Sheldon syndrome (FSS) who presented with ocular hypertension. The intraocular pressure (IOP) in his right eye progressively increased over time, leading to visual field loss, culminating in a diagnosis of juvenile-onset open-angle glaucoma (JOAG). Despite conventional medical therapies, adequate IOP control was not achieved, necessitating his referral to Nagoya City University Hospital.
View Article and Find Full Text PDFA Case of Long-Term Undiagnosed Cyclodialysis Cleft Following Tanito Microhook Trabeculotomy.
Cureus
January 2025
Department of Ophthalmology, Shimane University Faculty of Medicine, Izumo, JPN.
Persistent hypotony following Tanito microhook trabeculotomy (TMH) is rare but may occur due to the development of cyclodialysis clefts. We report a case of a Japanese man in his 40s who developed persistent hypotony and hypotony maculopathy after TMH in the left eye. Fourteen months after the surgery, the patient was referred to our institution due to prolonged hypotony that remained undiagnosed and untreated despite evaluations with gonioscopy and anterior segment optical coherence tomography (AS-OCT) at the referring clinic.
View Article and Find Full Text PDFAssociations between dementia and exposure to topical glaucoma medications.
J Alzheimers Dis
January 2025
Department of Ophthalmology, University of Washington, Seattle, WA, USA.
Background: Some studies have suggested that glaucoma may be associated with neurodegeneration and a higher risk of dementia.
Objective: To evaluate whether exposure to different categories of topical glaucoma medications is associated with differential dementia risks in people with glaucoma.
Methods: We used data from Adult Changes in Thought, a population-based, prospective cohort study that follows cognitively normal older adults from Kaiser Permanente Washington (KPWA) until Alzheimer's disease (AD) and related dementia development.
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