Purpose: The goal of this study was to better understand the safety and efficacy of CyberKnife image-guided radiosurgery for lesions immediately adjacent to the optic nerves.
Methods: This retrospective, non-comparative, interventional case series included 16 patients (6 women and 10 men) with lesions located wholly within the orbit. Thirteen cases involved tumors (31% benign and 69% malignant), two cases presented with chronic orbital inflammation and one patient had intraorbital tissue growth secondary to Graves disease. Staged radiosurgical ablation was performed using CyberKnife image-guided technology. The main outcome measures analyzed were change in tumor/neoplasm size, pain, visual field preservation and visual acuity, which were followed for up to 15 months.
Results: Twelve patients had a postoperative MRI, which revealed either a decrease or stabilization of tumor size. In the five lymphoma cases there was complete disappearance of the tumor. Pretreatment pain resolved in all 10 patients who reported it before the procedure; improvement in pain typically occurred within 1-2 weeks of radiosurgery. All 16 patients had a visual evaluation performed after the procedure: of these, 15 had no change in their visual field and one reported improvement. Visual acuity was preserved in 13 patients and improved in two, while one patient developed diplopia.
Conclusions: Staged CyberKnife radiosurgery is an effective option for the treatment of intraorbital lesions that controls tumor size, relieves pain, and preserves vision. The long-term safety of this treatment remains to be confirmed.
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http://dx.doi.org/10.1080/01676830601177471 | DOI Listing |
Radiol Case Rep
March 2025
Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, Morocco.
Inverted papilloma is a rare, benign epithelial tumor of the nasal and sinus cavities with an unclear etiology. It usually presents as unilateral nasal obstruction. Diagnosis is histological, and treatment is primarily surgical.
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November 2024
Applied Bioinformatics, German Cancer Research Center, Berliner Str. 41, 69120 Heidelberg, Germany.
Thyroid eye disease (TED) is a common extrathyroidal manifestation of hyperthyroidism, typically associated with Graves' disease (GD). This condition can cause severe functional limitations as well as significant aesthetic concerns. Treatment for TED patients aims to restore functionality and address aesthetic concerns.
View Article and Find Full Text PDFCureus
December 2024
Emergency Department, St Thomas' Hospital, London, GBR.
Intra-orbital organic foreign body injuries occur within the eye but without the involvement of the orbit itself. A 39-year-old man self-presented to the emergency department complaining of sudden onset of pain surrounding his left eye and of reduced vision. The initial examination was unremarkable except for two healing lesion marks above his left upper eyelid.
View Article and Find Full Text PDFArch Soc Esp Oftalmol (Engl Ed)
December 2024
Servicio Oftalmología, Hospital Alfredo Espinosa, Urduliz, Bizkaia, Spain.
A 66-year-old woman presents with unilateral orbital inflammation of several years of evolution, initially classified as idiopathic orbital inflammatory disease (IOID) subtype myositis. She presented with pain, eyelid inflammation and significant elevation of intraocular pressure, as well as radiological signs of exophthalmos and superior rectus myositis. She was treated with corticosteroids, with partial response.
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November 2024
Department of Ophthalmology and Visual Sciences, School of Medical Sciences, Universiti Sains Malaysia, Kota Bharu, MYS.
Sinonasal cancers are rare and aggressive head and neck malignancies. Sinonasal squamous cell carcinoma (SNSCC) typically affects males and individuals over the age of 55. Here, we present an unusual case of a young female diagnosed with SNSCC.
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