Envisioning a cooling method and aiming at maximum feasibility and simplicity, we designed an experimental intervention-control study based on non-refrigerated water usage, consisting of pouring 2 l of 23.0 degrees C water simultaneously on head and hands for one minute, after every 20 min of exertion. The subjects were 11 fit male individuals between 19 and 26 yr old. Each individual participated in one control and one intervention measurement in a climatic chamber at 35 degrees C and 60% humidity (31.5 degrees C WBGT) on different days. Heart rate, rectal, esophageal, skin and external ear canal temperatures were monitored constantly. Each experiment consisted of 10 min of basal recording followed by 3 intervals of 20 min of cycling and 15 min of rest. Stabilometry and visual reaction time tests were performed before and after each resting period. A questionnaire evaluating equilibrium, concentration, alertness and tiredness was administered at the beginning and at the end of every experiment. Paired t-test analysis revealed significant improvements in subjective parameters (all p<0.05), as well as skin (p<0.05), external ear canal (p<0.01) and esophageal (p<0.05) temperatures during the rest periods. Repeated measurement analysis of variance revealed significant cooling in all the aforementioned temperatures except the esophageal temperature (p=0.28). Other parameters were not significantly different. Our findings indicate that this method has subjective and physiologic positive effects, and thus can be used as a complementary low cost method to cool subjects safely.
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http://dx.doi.org/10.1539/joh.l7097 | DOI Listing |
Farm Hosp
July 2024
Servicio de Farmacia, Complexo Hospitalario Universitario de Pontevedra, Pontevedra, Spain.
Objective: To study the physicochemical and microbiological stability over 90 days of two preservative-free methylprednisolone sodium succinate (MTPSS) 1 and 10 mg/mL eye drops for use in ocular pathologies such as Sjögren's syndrome and dry eye syndrome.
Method: The two eye drops were prepared from injectable MTPSS (Solu-moderin® and Urbason®), water for injection and normal saline solution. In accordance with ICH (International Council for Harmonization of Technical Requirements for Pharmaceuticals for Human Use) guidelines, they were then stored in triplicate under refrigerated conditions (5±3 °C), at room temperature (25±2 °C), and at 40 °C (±2 °C).
Farm Hosp
July 2024
Servicio de Farmacia, Complexo Hospitalario Universitario de Pontevedra, Pontevedra, España.
Objective: To study the physicochemical and microbiological stability over 90 days of two preservative-free methylprednisolone sodium succinate (MTPSS) 1 mg/ml and 10 mg/ml eye drops for use in ocular pathologies such as Sjögren's syndrome and dry eye syndrome.
Method: The two eye drops were prepared from injectable MTPSS (Solu-moderin® and Urbason®), water for injection and normal saline solution. In accordance with ICH (International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use) guidelines, they were then stored in triplicate under refrigerated conditions (5 ±3 °C), at room temperature (25 ± 2 °C), and at 40 °C (±2 °C).
Microorganisms
December 2021
Riddet Institute, Massey University, Palmerston North 4442, New Zealand.
The stabilization of probiotics for application in non-refrigerated food products is a challenging task. In the present study, probiotic () ATCC 55544 cells were immobilized in a dairy matrix comprising of whole milk powder, skim milk powder, or milk protein isolate using fluidized bed drying technology. The samples were taken out at different drying stages, with an apparent water activity (a) of a 0.
View Article and Find Full Text PDFFood Res Int
November 2021
Laboratory of Food Microbiology and Hygiene, Department of Food Science & Technology, Faculty of Agriculture, Aristotle University, 54124 Thessaloniki, Greece. Electronic address:
A cardinal model (CM) for the effects of temperature (range: 32-59 °C), pH (range: 5.0-8.5) and water activity (a) (range: 0.
View Article and Find Full Text PDFAppl Microbiol Biotechnol
October 2021
Department of Entomology and Acarology, Escola Superior de Agricultura "Luiz de Queiroz, " University of São Paulo (ESALQ-USP), Av. Pádua Dias, 11, C.P. 9, Piracicaba, SP CEP, 13418-900, Brazil.
The present research addressed spray-drying and air-drying techniques applied to Metarhizium robertsii blastospores to develop wettable powder (WP) formulations. We investigated the effect of co-formulants on blastospore viability during drying and assessed the wettability and stability of formulations in water. The effect of oxygen-moisture absorbers was studied on the shelf life of these formulations stored at 26 °C and 4 °C for up to 90 days.
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