Background/aims: In physiotherapy, fango (mud) application is a frequently used heat therapy. The main therapeutic effects are due to the elevated temperature of the different tissues with a significant redistribution of blood towards the heated area. This may influence several cardiovascular parameters. There is only limited information on the effect of fango application on skin characteristics. It was the aim of the present study to evaluate the effects of fango application on skin temperature, perfusion of the microcirculation and skin colour. At the same time, cardiovascular parameters such as heart rate, systolic blood pressure (SBP) and diastolic blood pressure (DBP) were recorded.
Method: Eighteen healthy subjects (age 23.7+/-3.8 years) entered the study. The skin characteristics and cardiovascular parameters were measured before, during and after a 21-min fango application at 44.5 degrees C.
Results: Skin temperature and perfusion of the microcirculation increased significantly during fango application: from 35.5+/-0.4 degrees C to 44.3+/-1.2 degrees C for skin temperature and from 23.2+/-8.8 to 197+/-41 p.u. for the skin microcirculation. These two parameters remained elevated during the fango application and decreased slowly to baseline values within 21 min after fango removal. Skin colour (CIELAB, a(*) parameter) increased from 11.0+/-2.5 to 17.9+/-1.9 when comparing pre- with post-treatment values. At the end of the measuring period, the a(*) parameter did not return to baseline values (15.8+/-2.1). Heart rate increased with 8 bpm during the fango therapy and returned to baseline within 3 min after removal of the fango. SBP and DBP varied slightly during the fango application. They returned to baseline values within 21 min after fango removal.
Conclusion: The skin parameters indicate a transient temperature effect with an increased perfusion of the microcirculation and a flooding of the superficial capacitance system. The cardiovascular parameters were only slightly influenced and remained in the physiological range. Fango application seems not to be too demanding for the cardiovascular system in healthy subjects.
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http://dx.doi.org/10.1111/j.1600-0846.2007.00270.x | DOI Listing |
Front Epidemiol
January 2024
Department of Biology, Arba Minch University, Arba Minch, Ethiopia.
Background: Malaria is still a significant public health concern, and its prevention and control measures have different impacts in different areas. This study assesses the prevalence of malaria and the effectiveness of routine malaria control programmes such as indoor residual spray (IRS) in two Ethiopian villages.
Methods: The (villages) were purposefully selected based on their malaria prevalence rates.
Nanoscale
November 2015
School of Materials Science and Engineering, Gwangju Institute of Science and Technology, 261 Cheomdan-gwagiro, Buk-gu, Gwangju 500-712, Republic of Korea.
Effective delivery of nanoparticles to the target site is necessary for successful biomedical applications. Inefficient targeting is a major concern for nanomedicines in cancer therapy. Conjugation of multiple targeting ligands to the nanoparticle surface might further enhance the targeting efficiency by a co-operative effect of individual ligands.
View Article and Find Full Text PDFSmall
February 2010
Suzhou Institute of Nano-tech and Nano-bionics, Chinese Academy of Sciences, 398 Ruoshui Road, Dushu Lake Higher Education Town, Suzhou Industrial Park, Suzhou 215125, P. R. China.
A simple synthetic route for the preparation of functional nanoscale graphene oxide (NGO), a novel nanocarrier for the loading and targeted delivery of anticancer drugs, is reported. The NGO is functionalized with sulfonic acid groups, which render it stable in physiological solution, followed by covalent binding of folic acid (FA) molecules to the NGO, thus allowing it to specifically target MCF-7 cells, human breast cancer cells with FA receptors. Furthermore, controlled loading of two anticancer drugs, doxorubicin (DOX) and camptothecin (CPT), onto the FA-conjugated NGO (FA-NGO) via pi-pi stacking and hydrophobic interactions is investigated.
View Article and Find Full Text PDFSkin Res Technol
May 2008
Int. Akademie Physiotherapie Thim van der Laan, Landquart, Switzerland.
Background/aims: In physiotherapy, fango (mud) application is a frequently used heat therapy. The main therapeutic effects are due to the elevated temperature of the different tissues with a significant redistribution of blood towards the heated area. This may influence several cardiovascular parameters.
View Article and Find Full Text PDFPurpose: To investigate the curative effects of thermal water and thermal muds in various cutaneous pathologies.
Patients And Methods: Modifications of phmetry and sebometry using sulphur thermal muds in normal, dry and seborrheic skin have been studied. The three groups of patients have been submitted to a 14 day treatment with thermal muds.
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