A concise synthesis of maremycins A and D1 has been accomplished via cycloaddition of a chiral cyclic nitrone with ( E)-3-ethylidene-1-methylindolin-2-one as a key step. This synthesis clarifies the stereochemistry of the maremycins and is suitable for large-scale synthesis for biological screening.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/ol800515w | DOI Listing |
Publication Analysis
Top Keywords
synthesis maremycins
8
nitrone e-3-ethylidene-1-methylindolin-2-one
8
synthesis
4
maremycins cycloaddition
4
cycloaddition nitrone
4
e-3-ethylidene-1-methylindolin-2-one concise
4
concise synthesis
4
maremycins accomplished
4
accomplished cycloaddition
4
cycloaddition chiral
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!