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Evaluating Therapeutic and Chemical Toxicity Using Organ-Cultured Porcine Corneas and Epithelial Wound Healing.
J Vis Exp
January 2025
Departments of Ophthalmology and Anatomy and Cell Biology, Kresge Eye Institute, Wayne State University School of Medicine;
Due to its anatomical and physiological similarities to the human eye, the porcine eye serves as a robust model for biomedical research and ocular toxicity assessment. An air/liquid corneal culture system using porcine eyes was developed, and ex vivo epithelial wound healing was utilized as a critical parameter for these studies. Fresh pig corneas were processed for organ culture, with or without epithelial wounding.
View Article and Find Full Text PDFMg-B-O Coated P2-Type Hexagonal NaMnNiO as a High-Performance Cathode for Sodium-Ion Batteries.
ACS Appl Mater Interfaces
January 2025
National Base for International Science & Technology Cooperation, National Local Joint Engineering Laboratory for Key materials of New Energy Storage Battery, Hunan Province Key Laboratory of Electrochemical Energy Storage and Conversion, School of Chemistry, Xiangtan University, Xiangtan 411105, China.
P2-type NaMnNiO as the cathode for sodium-ion batteries, has a relatively high theoretical specific capacity, but its unstable crystal structure and undesirable phase transitions lead to rapid capacity decay. In this work, Mg-B-O coated NaMnNiO microspheres have been synthesized via a liquid-phase method based on solvothermal synthesized NaMnNiO. The Mg-B-O coating layer significantly improves the electrochemical performance, including specific capacity, rate capability, and cycle stability.
View Article and Find Full Text PDFSpecies- and strain-specific microbial modulation of interferon, innate immunity, and epithelial barrier in 2D air-liquid interface respiratory epithelial cultures.
BMC Biol
January 2025
The Jackson Laboratory for Genomic Medicine, Farmington, CT, 06032, USA.
Background: The microbiome regulates the respiratory epithelium's immunomodulatory functions. To explore how the microbiome's biodiversity affects microbe-epithelial interactions, we screened 58 phylogenetically diverse microbes for their transcriptomic effect on human primary bronchial air-liquid interface (ALI) cell cultures.
Results: We found distinct species- and strain-level differences in host innate immunity and epithelial barrier response.
Dynamic omniphobic surfaces enable the stable dropwise condensation of completely wetting refrigerants.
Nat Commun
January 2025
Department of Mechanical Science and Engineering, University of Illinois Urbana-Champaign, Urbana, IL, 61801, USA.
Condensation is a vital process integral to numerous industrial applications. Enhancing condensation efficiency through dropwise condensation on hydrophobic surfaces is well-documented. However, no surfaces have been able to repel liquids with extremely low surface tension, such as fluorinated solvents, during condensation, as they nucleate and completely wet even the most hydrophobic interfaces.
View Article and Find Full Text PDFFoaming ink for 3D-printing of ultralight and hyperelastic graphene architectures: Multiscale design and ultra-efficient electromagnetic interference shielding.
J Colloid Interface Sci
January 2025
School of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou 510006 China; Guangdong Provincial Laboratory of Chemistry and Fine Chemical Engineering Jieyang Center, School of Advanced Manufacturing, Guangdong University of Technology, Jieyang 515200 China. Electronic address:
Extrusion-based printing of macroscopic architectures layer-by-layer offers new opportunities for constructing customized electromagnetic interference (EMI) shielding materials. However, current research primarily focuses on improving the printability of material inks by increasing contents and adding various modifiers, controllable construction of ultralight and robust macro-architectures with structural design at both macro- and micro-scales is still challenging. Herein, we develop a graphene oxide foaming ink enriched with air bubbles for direct-ink writing, enabling the creation of macroscopic graphene architectures with arbitrary geometries.
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