From the fruits of Phaleria macrocarpa, icariside C(3) (1), phalerin (2), and mangiferin (3) were isolated and their structures were identified on the basis of spectroscopic data. Icariside C(3) (1) showed a slow vasorelaxant activity against noradrenaline-induced contraction of isolated rat aorta. The structure of phalerin (2) was revised as 2,4',6-trihydroxy-4-methoxybenzophenone-2-O-beta-D-glucoside.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s11418-007-0209-9 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Effect of Temperatures on Drying Kinetics, Extraction Yield, Phenolics, Flavonoids, and Antioxidant Activity of (Scheff.) Boerl. (Mahkota Dewa) Fruits.
Foods
July 2023
Faculty of Food Science and Nutrition, Universiti Malaysia Sabah, Jalan UMS, Kota Kinabalu 88400, Sabah, Malaysia.
(Scheff.) Boerl. or 'Mahkota Dewa' is a popular plant found in Malaysia as it is a valuable source of phytochemicals and therapeutic properties.
View Article and Find Full Text PDF(Scheff.) Boerl.: An updated review of pharmacological effects, toxicity studies, and separation techniques.
Saudi Pharm J
June 2023
Collaborative Laboratory for Herbal Standardization (CHEST), School of Pharmaceutical Sciences, Universiti Sains Malaysia, 11900 Bayan Lepas, Malaysia.
(Scheff.) Boerl. is geographically distributed around Papua Island, Indonesia.
View Article and Find Full Text PDFAngiotensin converting enzyme (ACE) inhibitors activity from purified compounds Fructus Phaleria macrocarpa (Scheff) Boerl.
BMC Complement Med Ther
February 2023
Departement of Pharmacy, Faculty of Health Sciences Universitas Esa Unggul, Jakarta, Indonesia.
Background: Mahkota Dewa [Phaleria macrocarpa (Scheff) Boerl.] fruit in vitro and in- vivo can decrease and prevent elevation of the blood pressure, lower plasma glucose levels, possess an antioxidant effect, and recover liver and kidney damage in rats. This study aimed to determine the structure and inhibitory activity of angiotensin-converting enzyme inhibitors (ACE) from the Mahkota Dewa fruit.
View Article and Find Full Text PDFIn Vitro, In Silico and Network Pharmacology Mechanistic Approach to Investigate the -Glucosidase Inhibitors Identified by Q-ToF-LCMS from Fruit Subcritical CO Extract.
Metabolites
December 2022
Borneo Research on Algesia, Inflammation and Neurodegeneration (BRAIN) Group, Department of Biomedical Sciences, Faculty of Medicines and Health Sciences, University Malaysia Sabah, Jalan UMS, Kota Kinabalu 88400, Sabah, Malaysia.
The fruit of have been traditionally used as an antidiabetic remedy in Malaysia and neighbouring countries. Despite its potential for diabetes treatment, no scientific study has ever been conducted to predict the inhibitor interaction of the protein -glucosidase identified in an extract prepared with a non-conventional extraction technique. Hence, the major aim of this research was to evaluate the in vitro antioxidant, the -glucosidase inhibitors, and the molecular dynamic simulations of the -glucosidase inhibitors identified by Quadrupole Time-of-Flight Liquid Chromatography Mass Spectrometry (Q-ToF-LCMS) analysis.
View Article and Find Full Text PDFExtraction and identification of biologically important proteins from the medicinal plant God's crown (Phaleria macrocarpa).
J Food Biochem
July 2021
Analytical Biochemistry Research Centre (ABrC), Universiti Sains Malaysia (USM), Bayan Lepas, Penang, Malaysia.
The fruit and leaf of God's crown (Phaleria macrocarpa) have been traditionally used to treat a wide variety of diseases. However, the proteins of this tropical plant are still heavily understudied. Three protein extraction methods; phenol (Phe), trichloroacetic acid (TCA)-acetone-phenol (TCA-A-Phe), and ultrasonic (Ult) were compared on the fruit and leaf of P.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!