A new prenylated dihydrochalcone from the leaves of Artocarpus lowii.

J Nat Med

Department of Chemistry, Faculty of Science, Universiti Teknologi Malaysia, UTM Skudai, 81310, Johor Bahru, Johor, Malaysia.

Published: July 2008

A new prenylated dihydrochalcone, 2',4'-dihydroxy-4-methoxy-3'-prenyldihydrochalcone (1), along with two known compounds, 2',4',4-trihydroxy-3'-prenylchalcone (2) and 2',4-dihydroxy-3',4'-(2,2-dimethylchromene)chalcone (3) were isolated from the leaves of Artocarpus lowii. The structures of 1-3 were elucidated by spectroscopic methods and by comparison with data reported in the literature. Compounds 1-3 showed strong free radical scavenging activity towards 2,2-diphenyl-1-picrylhydrazyl (DPPH) measured by electron spin resonance (ESR) spectrometry.

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http://dx.doi.org/10.1007/s11418-008-0226-3DOI Listing

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