The Centers for Disease Control and Prevention recently issued guidelines for medical examiners, coroners, and morticians in dealing with decedents after detonation of an improvised nuclear device (IND) or radiological dispersal device (RDD) (). Partners in this effort included the New York City Office of Chief Medical Examiner and the National Funeral Directors' Association. This paper describes the handling techniques required for loose surface contamination, radioactive shrapnel, and internal contamination caused by inhaling or ingesting radioactive materials from an IND or RDD, and provides suggested guidelines for medical examiners, coroners, and morticians to deal with these situations.
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http://dx.doi.org/10.1097/01.HP.0000300106.42165.ce | DOI Listing |
Alzheimers Dement
December 2024
Department of Psychiatry and Psychotherapy, Medical Faculty, University of Cologne, Cologne, Germany.
Background: Due to further development of diagnostic methods of early-stage diagnosis of Alzheimer's disease (AD) and new disease-modifying treatment options that require early diagnosis, a new focus on predictive and preventive medicine arises. With progress in AD dementia risk estimation, guidelines for counseling, considering individual aspects of those affected, are becoming more important. As part of the trinational project PreTAD (The Predictive Turn in Alzheimer's Disease: Ethical, Clinical, Linguistic and Legal Aspects) anticipated effects of AD dementia risk estimation for first-degree relatives of people with AD dementia are evaluated.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Hadassah Hebrew University Medical Center, Jerusalem, Israel.
Background: The cognitive reserve (CR) theory seeks to explain the mismatch often reported between brain damage and its clinical expression. Unlike most previous studies that focused on individuals with memory deterioration before the diagnosis of Alzheimer's disease (AD), the present study examined the late stages of the disease. The study sought to confirm the hypothesis that patients with higher CR are diagnosed later and decline faster than those with lower CR because their brain pathology is more severe.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Michigan Alzheimer's Disease Research Center, Ann Arbor, MI, USA.
Background: The integration of Large Language Models (LLMs) like ChatGPT-4 in clinical settings offers potential enhancements in medical practice, particularly in neurology and dementia care. There is rising public usage of ChatGPT-4 for preliminary information gathering. This study aims to evaluate the effectiveness of ChatGPT-4 in responding to neurology-focused queries, with an emphasis on Alzheimer's Disease (AD).
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Centre Mémoire de Ressources et de Recherches, Pôle de Neurosciences Cliniques, CHU de Bordeaux, Bordeaux, France.
Aims: The Alzheimer Association (AA) has proposed new diagnostic criteria for Alzheimer's disease (AD) based on biomarkers coinciding with β-amyloidosis onset. However, there are concerns regarding the implications of these criteria.
Methods: We reviewed several perspectives, including disease definition, public health, philosophy, therapeutic, and diagnostic.
Background: There are no evidence-based exercise guidelines to reduce falls in people living with dementia (PWD). The purpose of this pilot randomized controlled trial (RCT) was to determine the 1) feasibility and acceptability, and 2) effect of exercise on cognition and falls (exploratory) relative to usual care alone among PWD.
Methods: We randomized PWD to the exercise (n = 21) or usual care group (n = 21) at two residential care facilities in our pilot parallel, assessor-blinded RCT (1:1) [NCT05488951].
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