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Healthcare ethics and artificial intelligence: a UK doctor survey.
BMJ Open
December 2024
Centre for Social Ethics and Policy, Department of Law, School of Social Sciences, University of Manchester, Manchester, UK
Article Synopsis
- The study surveyed 272 UK doctors about their use of artificial intelligence (AI) in healthcare, focusing on their knowledge, concerns, and views on regulation.
- Most doctors felt they had limited knowledge of AI, with men rating themselves higher than women, and younger doctors in training were more likely to use AI compared to more experienced doctors.
- Concerns about AI included patient safety and confidentiality, leading to a strong call from doctors for more regulatory guidelines from professional bodies regarding AI usage in their practices.
Are cathepsins a risk factor for papillary thyroid carcinoma? A bidirectional two-sample mendelian randomization analysis.
Eur Arch Otorhinolaryngol
January 2025
Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, 550004, China.
Article Synopsis
- Papillary thyroid carcinoma (PTC) is the most common endocrine tumor, and the rise in its incidence may be linked to cathepsins, which are proteins thought to influence tumor progression.
- A study used Mendelian randomization to analyze data on cathepsins and PTC, finding a significant association with cathepsin Z (CTSZ) increasing the risk of PTC, while reverse causality was not supported.
- The results suggest that CTSZ could be a potential marker for predicting and diagnosing PTC early, and may inform future therapeutic approaches targeting this protein.
A Graphene-Based Bioactive Product with a Non-Immunological Impact on Mononuclear Cell Populations from Healthy Volunteers.
Nanomaterials (Basel)
December 2024
Department of Systems Biology, Universidad de Alcalá, Instituto Ramon y Cajal de Investigación Sanitaria, Fundación Renal Iñigo Álvarez de Toledo, 28871 Alcalá de Henares, Spain.
We previously described GMC, a graphene-based nanomaterial obtained from carbon nanofibers (CNFs), to be biologically compatible and functional for therapeutic purposes. GMC can reduce triglycerides' content in vitro and in vivo and has other potential bio-functional effects on systemic cells and the potential utility to be used in living systems. Here, immunoreactivity was evaluated by adding GMC in suspension at the biologically functional concentrations, ranging from 10 to 60 µg/mL, for one or several days, to cultured lymphocytes (T, B, NK), either in basal or under stimulating conditions, and monocytes that were derived under culture conditions to pro-inflammatory (GM-MØ) or anti-inflammatory (M-MØ) macrophages.
View Article and Find Full Text PDFA review of consent policies in Dermatological Surgery in the United Kingdom and the impact of leaner pathways and teledermatology on consent.
Clin Exp Dermatol
November 2024
Department of Dermatology, Walsall Healthcare NHS Trust, UK.
Obtaining valid consent is an ethical and legal requirement in clinical practice, ensuring patients are adequately informed about their treatments. Recent updates in consent policies, including GMC guidance, the Patterson inquiry report, and key legal rulings like Montgomery, emphasise a shift towards patient-centred care and the importance of a comprehensive patient-clinician dialogue. Budget constraints and increasing NHS demand have led to the adoption of digital solutions and streamlined pathways, such as teledermatology and direct booking to surgery, potentially compromising the consent process.
View Article and Find Full Text PDFPractices of Informed Written Consent for Elective Urological Procedures at a Tertiary Care Hospital in Sudan.
Cureus
September 2024
Urology, Military Hospital, Khartoum, SDN.
Objective This study aimed to assess informed consent practices in elective urological surgeries at a tertiary care facility. Materials and methods A retrospective cross-sectional survey was carried out between March 1, 2023 and April 1, 2023, at the Department of Urology, Omdurman Military Hospital, Sudan. We included all patients who had undergone elective urological procedures under local, spinal, or general anesthesia.
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