This research is a follow up of a Breast Week which was organized in Freetown, Sierra Leone. The specific objective of this study was to assess the effectiveness of the knowledge and teachings given to the women who participated in this project. A quantitative approach with an exploratory descriptive design was adopted and an observational checklist guided the data collection process. A sample size of 120 women (10%) who participated in the Breast Week was obtained through systematic sampling. During the Breast Week women were taught how to examine their breasts using breast self-examination (BSE) to detect abnormalities of the breasts. This study was undertaken one year later by the researcher to ascertain whether the information on breast self-examination provided during the Breast Week was being utilised and whether what was taught was being put into use. Data were analyzed using SPSS version 11.5. Reliability and validity were ensured through the use of a structured observational checklist and a pilot study was undertaken. The observations were all observed and recorded by the same researcher. The majority of the 120 women (91.7%) stated that they had never practiced BSE before the Breast Week. After receiving health education on BSE, 95% were able to demonstrate an effective method of undertaking BSE. It is thus recommended that every opportunity should be utilized in health care settings to teach BSE and to reinforce the practice, especially in poverty stricken countries where other forms of screening methods are unavailable.
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http://dx.doi.org/10.4102/curationis.v30i4.1115 | DOI Listing |
JAMA Oncol
January 2025
Department of Surgery, University of California, San Francisco.
Importance: Intratumoral immunotherapy that leverages the biological characteristics of high-risk ductal carcinoma in situ (DCIS) may be able to reduce the extent of surgical treatment and provide an alternative approach to improve patient outcomes.
Objective: To determine if combination intratumoral immunotherapy can activate immune cells to shrink or eliminate high-risk DCIS.
Design, Setting, And Participants: This phase 1 open-label nonrandomized clinical trial at a single academic center tested the safety and efficacy of intratumoral immunotherapy in patients with high-risk DCIS, defined as at least 2 of the following present: younger than 45 years, tumor size greater than 5 cm, high-grade, palpable mass, hormone receptor (HR)-negative, or ERBB2-positive.
Poult Sci
January 2025
State Key Laboratory of Livestock and Poultry Breeding, Guangdong Provincial Key Laboratory of Animal Nutrition and Regulation, College of Animal Science, South China Agricultural University, Guangzhou 510000, PR China. Electronic address:
Good skin quality not only improved carcass quality but also increased consumer demand for fresh poultry meat. This study aimed to investigate the developmental changes in skin growth and quality of Pekin ducks during 1-6 weeks of age. The skin samples were collected from the breast, back, and thigh tissues of six male ducks at the end of each week.
View Article and Find Full Text PDFSupport Care Cancer
January 2025
Department of Social Sciences and Health Policy, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Purpose: To describe physical activity (PA) trajectories across 10 years post-breast cancer diagnosis and examine their association with quality of life (QoL).
Methods: Participants from the longitudinal Study of Women's Health Across the Nation who developed incident breast cancer completed the Quality of Life in Adult Cancer Survivors scale (QLACS) which has 12 domains. Breast cancer survivors (BCS) with at least one post-diagnosis measure of the Kaiser Physical Activity Survey (PA) were included (n = 96).
Nat Commun
January 2025
State Key Laboratory of Drug Research & Center of Pharmaceutics, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
The efficacy of cancer immunotherapy relies on a sufficient amount of functional immune cells. Triple-negative breast cancer lacks enough immune cell infiltration, and adjuvant therapy is necessary to prime anti-tumor immunity. However, the improvement in efficacy is unsatisfactory with concern about inducing systemic immunotoxicity.
View Article and Find Full Text PDFEur J Oncol Nurs
January 2025
Department of Health Disparities Research, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address:
Purpose: Rural breast cancer survivors (BCS) have unique unmet psychosocial needs that affect quality of life (QOL). Expressive writing (EW) has been shown to improve QOL in cancer survivors, however, its applicability is unclear among rural individuals. This pilot study explores the feasibility and acceptability of an online expressive writing (EW) intervention among rural breast cancer survivors (BCS).
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