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Presentation and Surgical Outcomes of Primary Hyperparathyroidism After Radioactive Iodine Therapy.
J Surg Res
January 2025
Department of Surgery, Washington University School of Medicine, Saint Louis, Missouri.
Background: Radioactive iodine (RAI) is a common treatment for various thyroid diseases. Previous studies have suggested susceptibility of parathyroid glands to the mutagenic effect of RAI and the development of primary hyperparathyroidism (PHPT). We tested the possible link between prior RAI treatment, disease presentation, and treatment outcomes.
View Article and Find Full Text PDFComparative effectiveness of various orbital decompression techniques in treating thyroid-associated ophthalmopathy: a systematic review and meta-analysis.
BMC Ophthalmol
December 2024
Beijing Tongren Eye Center, and Beijing Ophthalmology Visual Science Key Lab, Beijing Tongren Hospital, Capital Medical University, No.1 Dong Jiao Min Xiang, Beijing, 100730, China.
Background: In thyroid-associated ophthalmopathy (TAO), orbital decompression is a critical surgical approach for functional and aesthetic reasons. Meanwhile, the presence of surgical complications, especially the new onset of primary gaze diplopia, also influences postoperative patient satisfaction. This research investigates the effectiveness and potential risks associated with different orbital decompression in patients with TAO.
View Article and Find Full Text PDFIsolated Mediastinal Goitre: A Case Report.
Indian J Otolaryngol Head Neck Surg
August 2024
Department of Surgical Oncology, Nizams Institute of Medical Sciences, 4th floor, Specialty Block, Hyderabad, 500082 Telangana India.
Unlabelled: Retrosternal goitre is not an uncommon entity owing to various reasons - ignorance, fear, lack of access to safe surgical technique, incomplete thyroid surgery. Retrosternal goitre could have varied presentations, especially in cases with prior thyroid surgery. Fifty-three-year-old female with history of thyroid surgery 20 years back presented with a large neglected anterior neck swelling.
View Article and Find Full Text PDFTreatment Patterns and Preferences for Graves' Disease in Korea: Insights from a Nationwide Cohort Study.
Endocrinol Metab (Seoul)
August 2024
Division of Endocrinology and Metabolism, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
Treatment patterns and preferences for patients with Graves' disease (GD) vary across countries. In this study, we assessed the initial therapies and subsequent treatment modalities employed for GD in real-world clinical practice in Korea. We analyzed 452,001 patients with GD from 2004 to 2020, obtained from the Korean National Health Insurance Service database.
View Article and Find Full Text PDFCase report: Propylthiouracil-induced serious side effect: Perinuclear antineutrophil cytoplasmic antibody-associated vasculitis or IgA vasculitis?
Medicine (Baltimore)
July 2024
Department of Nephrology, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, Zhejiang, China.
Article Synopsis
- Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a rare inflammatory disease linked to small blood vessels, often triggered by antithyroid drugs like propylthiouracil (PTU) in patients with Graves' disease.
- A case report of a female patient planning pregnancy highlighted the development of PTU-induced p-ANCA-associated vasculitis, leading to joint pain and kidney issues, evidenced by autoimmune markers.
- The patient was treated with glucocorticoids and immunosuppressive therapy, showing improvement in kidney and thyroid function, emphasizing the need for careful consideration of medication and pregnancy planning in similar cases.
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