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Secreted extracellular heat shock protein gp96 and inflammatory cytokines are markers of severe malaria outcome.
Cell Stress Chaperones
December 2024
Unite postulante de Biologie Genetique, Genomique et Bio-informatique (G2B), Departement de Biologie animale, Faculté des Sciences et Techniques, Universite Cheikh Anta DIOP, Avenue Cheikh Anta DIOP, BP: 5005, Dakar, Senegal. Electronic address:
Malaria caused by Plasmodium spp., is a major public health issue in sub-Saharan Africa. The fight against malaria has stalled due to increasing resistance to treatments and insecticides.
View Article and Find Full Text PDFPredictive modeling of diazinon residual concentration in soils contaminated with potentially toxic elements: a comparative study of machine learning approaches.
Biodegradation
December 2024
Department of Civil engineering, Islamic Azad university, Mashhad Branch, Iran.
The widespread use of pesticides, including diazinon, poses an increased risk of environmental pollution and detrimental effects on biodiversity, food security, and water resources. In this study, we investigated the impact of Potentially Toxic Elements (PTE) including Zn, Cd, V, and Mn on the degradation of diazinon in three different soils. We investigated the capability and performance of four machine learning models to predict residual pesticide concentration, including adaptive neuro-fuzzy inference system (ANFIS), support vector regression (SVR), radial basis function (RBF), and multi-layer perceptron (MLP).
View Article and Find Full Text PDFSynergistic Anxiolytic Effects of Linalool and Sesamol Co-Treatment on Swiss Albino Mice: A Potential GABAergic Intervention.
Synapse
January 2025
Department of Biochemistry & Molecular Biology, Bangabandhu Sheikh Mujibur Rahman Science and Technology University, Gopalganj, Bangladesh.
Sesamol (SES) and linalool (LIN) are aromatic compounds that have neuroprotective effects. The main purpose of this study is to evaluate the anxiolytic activity of LIN and SES co-treatment on Swiss albino mice and analyze its possible mechanism through in silico study. In this sense, the mice were given the gamma-aminobutyric acid type A receptors (GABA) agonist diazepam (DZP; 3 mg/kg, p.
View Article and Find Full Text PDFAssessing the Influence of Low Doses of Sucrose on Memory Deficits in Fish Exposed to Common Insecticide Based on Fipronil and Pyriproxyfen.
Curr Issues Mol Biol
December 2024
Research and Development Station for Aquaculture and Aquatic Ecology, "Alexandru Ioan Cuza" University, Carol I, 20A, 700505 Iasi, Romania.
Although pesticides have been a constant concern for decades, in the last ten years, public discussions and scientific research have emphasized their impact on human health and the environment, drawing increased attention to the problems associated with their use. The association of environmental stressors such as pesticides with a sugar-rich diet can contribute to the growing global metabolic disease epidemic through overlapping mechanisms of insulin resistance, inflammation, and metabolic dysregulation. The main aim of this study was to evaluate the behavioral effects of the exposure of Silver crucian carp () to a commercial insecticide formulation containing fipronil, pyriproxyfen, and other additives, as well as sucrose and their mixtures.
View Article and Find Full Text PDFA novel dataset and deep learning object detection benchmark for grapevine pest surveillance.
Front Plant Sci
December 2024
Research and Innovation Centre, Fondazione Edmund Mach, San Michele all'Adige, TN, Italy.
Flavescence dorée (FD) poses a significant threat to grapevine health, with the American grapevine leafhopper, , serving as the primary vector. FD is responsible for yield losses and high production costs due to mandatory insecticide treatments, infected plant uprooting, and replanting. Another potential FD vector is the mosaic leafhopper, , commonly found in agroecosystems.
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